Team:HIT-Harbin/project/notebook/diary

Light controlling protein as a switch to regulate expression. –Ying ZHANG
Application for water pollution. –Yongqian HE
Engineering helicobacter pylori for medical application. –Yubo YANG
Synthesis biology of plant hormones. –Yifan WU
On 04/21

Biology compass. --Lei QIAO
Engineering bacteria for carbon dioxide fixation. –Fangping XIE
Biosensor. –Borong CHENG
Culture of magnetotactic bacteria, heavy work. –Kunming ZHAO
On 04/28

Introduction of Matlab, Cell Designer, Biosimulation for modeling. –Yue YU
miRNA for mRNA silence, for anticancer usage. –Fangping XIE
Microbial electricity generation. –Minghui HUANG
Protein modification for cancer treating. –Xiangmiao ZENG
Quorum sensing to detect enterovirus. –Lei QIAO
0n 05/12

Invitation of a professor from Zhejiang University researching in synthesis biology.
A database software for everyone who’d like to collect the data of previous team information.
Create a flash showing the sprite of iGEM and the team of HIT.
Cartoon for spread of iGEM and synthesis biology around Harbin Institute of Technology.
In early June

Song adaptation have done by Yifan WU, also made a flash linked to the Internet for sharing the iGEM happiness.
Made the first version of database software, which provides for SQL querying. But the database only includes teams from America.
In mid-July

1. Memristor and some other electric devices by engineered bacteria.
2. Biofilm from cellulose degradation.
3. Microbial fuel cell from bacteria in industrial wastewater.
4. Environmental detection, Enterovirus.
On 05/18

Speech given by Prof. CHEN from Zhejiang University
For introduce synthesis biology and iGEM latest hot research.
Two lectures in the Huanghe Road campus and the main campus.
After the lecture, we made recruitment of new members for iGEM_HIT.
In early March

Prof. XU attending the meeting for biology modeling training.
Flux balance analysis (FBA) is a widely used approach for studying biochemical networks, in particular the genome-scale metabolic network reconstructions.
FBA is a powerful mean of biological metabolic networks.
The process of iGEM is design-modelling-experiment-design again.
Three methods:
System definition, Mass balance; Linear programming regulation
On 05/26

Song adaptation have done by Yifan WU, also made a flash linked to the Internet for sharing the iGEM happiness.
Made the first version of database software, which provides for SQL querying. But the database only includes teams from America.
In mid-July

We searched plenty of publications for which related to mathematical modeling.
And two modeling members took responsible of each main part, detecting and killing, begin with figure out gene expression regulation.
For the next step, learning modeling software is necessary; we decided to use Matlab for main platform combining with other tools, such as cell designer.
In mid-July

Figure out the regulation of detecting device in mathematical method.
Peruse the related literatures to conclude the Ordinary Differential Equations for our novel design.
Simulation in matlab for getting the material curve and analyse the results.
In late July

Work out the regulation of killing device in mathematical method.
Conclude the Ordinary Differential Equations for our novel design from literatures.
Analyse the results from matlab curves of species variation.
Model improvement of the former part. Change the parameter of ODEs.
In early August

Ying ZHANG concluded the software team of Berkeley in 2009, who build the platform for tools development of other researchers and teams.
Fangping XIE introduced the software team of USTC 2011. He elaborated the novel data structure which is named “Chain Node” model.
In June

Reference to the former HIT_Harbin team wiki:
https://2011.igem.org/Team:HIT-Harbin
Best wiki of three areas：
https://2011.igem.org/Team:Calgary
https://2011.igem.org/Team:HokkaidoU_Japan
https://2011.igem.org/Team:Imperial_College_London
In Mid-September

To design a logo which can show the spirit of our team. At last, ZHAO Kunming chose the windmill as the main part. One side, the blades can symbolize the biobricks, and these biobricks assemble a completed system which begins to ‘run’, the other side, the blades stand for the team which consisted of us coming from different majors that can make the work ‘run’.
In Mid-June

After drawing the comic, we discussed and chose the color of the T-shirts. Then we went to the cloths shop several times to make the T-shirts and got what we wanted at last. ZHAO Kunming contributes a lot in this work.
In September