Team:Harvey Mudd/Notebook
From 2012.igem.org
(Prototype team page) |
Jwentworth (Talk | contribs) m |
||
(2 intermediate revisions not shown) | |||
Line 31: | Line 31: | ||
- | You should make use of the calendar feature on the wiki and start a lab notebook. This may be looked at by the judges to see how your work progressed throughout the summer. It is a very useful organizational tool as well. | + | From iGEM: You should make use of the calendar feature on the wiki and start a lab notebook. This may be looked at by the judges to see how your work progressed throughout the summer. It is a very useful organizational tool as well. |
+ | |||
+ | We might do that eventually. For now, we can keep track of progress here. | ||
+ | |||
+ | 6/4: Last night I finally proved uniqueness for the steady-state equations for TALOR systems. The good news: that's done. The bad news: TALORs cannot build bistable systems without some other component. The model used also applies to TFOs. | ||
+ | |||
+ | 6/19: A 1991 paper [http://pubs.acs.org/doi/abs/10.1021/ja00015a076 reported] successful use of TFOs with regions designed to dimerize. The two TFOs form a much more stable triplex after dimerization, exactly as needed for bistable circuit design. The downside is that it requires DNA oligos, and I have no idea how those come about in vivo. |
Latest revision as of 19:29, 21 June 2012
Home | Team | Official Team Profile | Project | Parts Submitted to the Registry | Modeling | Notebook | Safety | Attributions |
---|
From iGEM: You should make use of the calendar feature on the wiki and start a lab notebook. This may be looked at by the judges to see how your work progressed throughout the summer. It is a very useful organizational tool as well.
We might do that eventually. For now, we can keep track of progress here.
6/4: Last night I finally proved uniqueness for the steady-state equations for TALOR systems. The good news: that's done. The bad news: TALORs cannot build bistable systems without some other component. The model used also applies to TFOs.
6/19: A 1991 paper [http://pubs.acs.org/doi/abs/10.1021/ja00015a076 reported] successful use of TFOs with regions designed to dimerize. The two TFOs form a much more stable triplex after dimerization, exactly as needed for bistable circuit design. The downside is that it requires DNA oligos, and I have no idea how those come about in vivo.