Team:Harvey Mudd/Notebook


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From iGEM: You should make use of the calendar feature on the wiki and start a lab notebook. This may be looked at by the judges to see how your work progressed throughout the summer. It is a very useful organizational tool as well.

We might do that eventually. For now, we can keep track of progress here.

6/4: Last night I finally proved uniqueness for the steady-state equations for TALOR systems. The good news: that's done. The bad news: TALORs cannot build bistable systems without some other component. The model used also applies to TFOs.

6/19: A 1991 paper reported successful use of TFOs with regions designed to dimerize. The two TFOs form a much more stable triplex after dimerization, exactly as needed for bistable circuit design. The downside is that it requires DNA oligos, and I have no idea how those come about in vivo.