From 2012.igem.org

Latest revision as of 01:31, 27 September 2012

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  • 1. Introduction
  • 2. PnA System
  • 3. Virus-Like Particles
    • CCMV
    • HepB
    • Polerovirus Natural BioBrick
  • 4. Outside Modification
  • 5. Inside Modification
  • 6. Detection of VLPs
  • 7. Applications
  • 8. The Constructor
  • 9. Final Overview
• Human Practices
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  • 1. Mini Symposium
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  • 3. Discovery Festival
    • Communication Science
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  • 5. Munich CAS Conference
• Safety
  • Introduction
  • 1. General safety
  • 2. Virus-related safety
  • 3. Regulations
  • 4. Safety suggestions
  • 5. Safety of applications
• Modeling
  • Human Body Model
  • Tertiary folding prediction
  • VLP assembly model
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Last year's project: Synchronized Oscillatory System

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week 0: A new beginning

A short history of team Wageningen UR 2012

During the final weeks of 2011, our supervisors gathered a small group of enthusiastic students, willing to sacrifice their summer holiday to work on iGEM. In the first weeks of January, this small group quickly expanded to about 10 persons who were involved in the brainstorm.
A Belgium Beer Café was deemed most suitable for this purpose. The ideas that came to our minds were everything in between brilliant and alcohol induced nonsense.

Having a beer while brainstorming at De Vlaamsche Reus

Interesting to notice, our final idea is derived from the first idea on our brainstorm list, which can be inspected at the bottom. The Google drive document indicated on September 5, 2012:

A screenshot from the google drive, indicating the time between the start of our brainstorm and the final weeks of the project

During the months February and March, we trimmed the list down to only 3 ideas: - Site specific drug delivery using VLPs - Mimicking eukaryotic glycosylation patterns in prokaryotes - Conversion of Polycyclic Aromatic Hydrocarbons into usable chemicals After consultation of postdocs and (associate) professors of both Wageningen University and elsewhere, we had a vote which ended in a tie between drug delivery and glycosylation. After a second consultation round and additional information about glycosylation from Prof. Markus Aebi (ETH Zurich), we decided to choose for the site specific drug delivery using VLPs. The final decision was based upon feasibility of the project within the given timeframe. The comment of Aebi was that we are “somewhat ahead of our time”.

The Ideas

1. A Site specific drug delivery (epithelial cancer)
2. A Organic sphere lighting
3. A Ground erosion
4. A Eating plastics
5. A Producing oil
6. A Nice smelling farts (like flowers)
7. Biological clock
8. Deodorant
9. Red foam on beer
10. Toxic sensors (promotor induced by toxins)
11. Detection of radiation, Fukushima
12. ZOAB-saving bacteria. Filling cracks, reacting on exposure to air.
13. Glycerol production to prevent freezing
14. Taste customisation by temperature controlled promotors. Each temperature yields a different taste.
15. Fermentation of drinks (orange juice to cocktails) (in teabag)
16. Beef production by MOs. (flavours)
17. Waste product degradation and production of usable products
    1. Recycling of phosphates
    2. Bacteria for urinals: decrease smell and convert to usable product in sewage stream.
18. Bird flu 4.0, deathly
19. Bacteria that eat: Houses, batteries, death terrorists
20. Bomb detection
21. Dog nose bacteria
22. Land mine detection (explosives)
23. Production of bomb ingredients
24. Drugs detector
25. Alcohol detection, save to drive?
26. Liver damage detection in urine
27. Cancer detection in urine, diabetes, STDs and other diseases (at home)
28. Condom that lights up when in contact with STD
29. Batteries by MOs (rechargeable)
30. Biodegradable batteries
31. Collecting gold
32. Hydrogen production
33. Accumulation of metals from seawater in bacteria (recycling)
34. Accumulation of salt from sea water or flocculation of salt
35. Lights up when low in alcohol, you should drink more
36. Anti-hangover
37. Food preservation
38. Fat binding E. coli, loosing weight
39. Degradation of pesticides
40. Bio diesel
41. CO2, methane fixation
42. Methane degradation in cows. Convert it into usable fuel, less greenhouse gas
43. Flying bacteria
44. Biofilm around the world
45. Bacterial catalysers in cars (recycling)
46. Produce shoe polish when exposed to air
47. Cleaning with bacteria
48. Bacteria that convert food into medicine (in situ)
49. Music, sound producing MOs
50. Vibrating MOs that store music
51. Production of wood
52. Reversed humans for in space
53. Rocket fuel
54. Glue/Duct tape
55. Cooling, cleaning air: Climate control.
56. Bone replacement
57. Kill mosquitoes
58. Kill vectors for diseases (malaria by killing mosquitoes)
59. Fresh water production
60. Plastic/spider silk production
61. MOs eating hair pockets (no shaving anymore)
62. LSD production
63. In situ production of narcotics. Helping addicts
64. Binding of sex hormones, pedofile detector
65. Viagra producing fungi
66. Sterilisation bacteria (birth control)
67. Fortification of dykes
68. Cell Cycle Control by using mono-chromatic light
69. Cell Cycle Control by using inducer (nisin or subtilin)
70. Plastic degrading bacteria in ocean
71. Bio memory
72. Bio computer/intelligence
73. Rapid Evolution Micro-Organism
74. Protein deficiency solution using micro-organisms symbiosis
75. Hormone misbalance solution using micro-organism symbiosis
76. Vitamin deficiency solution using Micro-organism symbiosis
77. Mono-chromatic light as inducer
78. Walking light cell line
79. Minimal cell
80. Garbage micro-organism
81. Micro-organism growing (only) on (exaust) gasses
82. Plastics to fuel
83. Agricultural waste to plastics
84. Polymer production by using peptidoglycan layer producing units
85. Extreme symbiotic cells
86. Micro-organism reacting to sound/vibrations
87. Cell line production
88. The Exploding Cells Infection
89. Bodily fluids clean up
90. Faeces to plastics
91. Survival cell
92. Hazardous material detector and quantifier

[next week]