"
Team:Freiburg
From 2012.igem.org
(Difference between revisions)
| Line 10: | Line 10: | ||
| | | | ||
''Stay tuned to FreiGEM 2012 - we will keep you in the loop.'' | ''Stay tuned to FreiGEM 2012 - we will keep you in the loop.'' | ||
| - | |[[Image:Freiburg_team.png| | + | |} |
| + | {| | ||
| + | |[[Image:Freiburg_team.png|left|no frame|The FreiGEM 2012 Team]] | ||
|- | |- | ||
| | | | ||
| - | |||
|} | |} | ||
<!--- The Mission, Experiments ---> | <!--- The Mission, Experiments ---> | ||
| - | + | {|align="justify" | |
| + | |[[Image:balken.png|950px|left|no frame]] | ||
| + | |} | ||
{| style="color:#10b0c5a;background-color:#0b4c10a;" cellpadding="5" cellspacing="2" border="0" bordercolor="#fff" width="80%" align="left" | {| style="color:#10b0c5a;background-color:#0b4c10a;" cellpadding="5" cellspacing="2" border="0" bordercolor="#fff" width="80%" align="left" | ||
!align="center"|[[Team:Freiburg|Home]] | !align="center"|[[Team:Freiburg|Home]] | ||
Revision as of 09:42, 8 May 2012
 |
 |
| The iGEM Team Freiburg 2012 (FreiGEM) is dedicated to standardize the synthesis of Transactivator-like (TAL) proteins, i.e. DNA-binding proteins. In contrast to zinc-finger proteins they consist of domain-like repeats in their primary structure that differ only by two amino acids. These two amino acids of a given repeat determine which DNA base the repeat will bind to. By providing efficient mechanisms to combine the different repeats in order to target a certain DNA sequence of around 14bp the FreiGEM team is working towards establishing a standardized kit. This one tube essay will provide the user with an easy, quick and cost-efficient way to design his or her individualized TAL protein in just a glance. However, FreiGEM 2012 will not stop there but move beyond that by also including different TAL effectors in the kit. These are enzymes that can be linked to the DNA-binding domain and thereby act only around a specific region in the genome - perefectly suited for epigenetic application, for instance by using histone modifying enzymes. |
|
Stay tuned to FreiGEM 2012 - we will keep you in the loop. |
|
| Home | Team | Official Team Profile | Project | Parts Submitted to the Registry | Modeling | Notebook | Safety | Attributions |
|---|
