Team:USTC-China

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  <a href="https://2012.igem.org/Team:USTC-China/team">Team
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<P>WELCOME TO THE WIKI OF USTC-CHINA IGEM TEAM! ENJOY YOUR EXPLORATION!</P>
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<p class="button">We have theoretically analysed our system through Mathematical Modeling!</p>
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<a href="https://2012.igem.org/Team:USTC-China/outreach">OUTREACH</a>
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<p class="button">Our team have conducted several activities for public recognition of synthetic biology!</p>
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<p class="button2">Members in USTC_China enjoyed themselves this summer!</p>
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<p class="project">Bacteriophage is one of the severest threats to fermentation factories. To help solve the problem, we design a gene circuit which can both sense and defend against phages. We use the modified promoter pRM to sense the phage’s infection and initiate the defence. The lysis gene which can make bacteria lyse is installed to our circuit. When it works, the phage won’t be able to take advantage of its host to replicate any longer. To win more time for lysis to function well, we design an antisense RNA to prevent the phage from turning into lytic life cycle. Thus, when the lysis protein kills the host, the phage is still at lysogenic life cycle or the newly assembled phages are still immature. By using the quorum sensing system, the bacteria around the host can make well preparation to defend in advance. Attribute to these parts, our bacteria survive.</p>  
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  <a href="http://china.db.com/" style="float:left;margin-left:10px;"><img src="https://static.igem.org/mediawiki/2012/0/0c/Deutsche_bank.jpg" /></a>
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  <a href="http://www.ustcif.org/" ><img src="https://static.igem.org/mediawiki/2012/3/36/Ustcif.jpg" style="height:99px;width:98px;float:left;margin-left:10px;"/></a>
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  <a href="http://en.gradschool.ustc.edu.cn/" ><img src="https://static.igem.org/mediawiki/2012/7/79/GRADUATE.png" style="float:left;margin-left:10px;"/></a>
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  <a href="http://www.teach.ustc.edu.cn/" style="float:left;margin-left:10px;"><img src="https://static.igem.org/mediawiki/2012/7/79/Teaching.jpg" /></a>
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  <a href="http://en.biox.ustc.edu.cn/" style="float:left;margin-left:10px;"><img src="https://static.igem.org/mediawiki/2012/archive/5/5e/20120830175936%21Life.jpg" /></a>
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  <a href="http://en.physics.ustc.edu.cn/" style="float:left;margin-left:10px;"><img src="https://static.igem.org/mediawiki/2012/a/ac/Phy.png" /></a>
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  <a href="http://en.scgy.ustc.edu.cn/" ><img src="https://static.igem.org/mediawiki/2012/f/f1/Gifted_young.jpg" style="width:330px;height:85px;float:left;margin-left:10px;"/></a>
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Latest revision as of 03:21, 28 September 2013

WELCOME TO THE WIKI OF USTC-CHINA IGEM TEAM! ENJOY YOUR EXPLORATION!

PARTS

This summer we have contributed 22 parts to the partsregistry!

MODELING

We have theoretically analysed our system through Mathematical Modeling!

OUTREACH

Our team have conducted several activities for public recognition of synthetic biology!

SAFETY

The project is considered to have the minimal risks!

TEAM

Members in USTC_China enjoyed themselves this summer!

WELCOME!

Bacteriophage is one of the severest threats to fermentation factories. To help solve the problem, we design a gene circuit which can both sense and defend against phages. We use the modified promoter pRM to sense the phage’s infection and initiate the defence. The lysis gene which can make bacteria lyse is installed to our circuit. When it works, the phage won’t be able to take advantage of its host to replicate any longer. To win more time for lysis to function well, we design an antisense RNA to prevent the phage from turning into lytic life cycle. Thus, when the lysis protein kills the host, the phage is still at lysogenic life cycle or the newly assembled phages are still immature. By using the quorum sensing system, the bacteria around the host can make well preparation to defend in advance. Attribute to these parts, our bacteria survive.


more

SPONSORS


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