Team:USTC-China

From 2012.igem.org

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Revision as of 14:17, 22 September 2012

WELCOME TO THE WIKI OF USTC-CHINA IGEM TAEM! ENJOY YOUR EXPLORATION!

PARTS

this summer we have attributed several parts to the partsregistry!

MODELING

We have theoretically analyse our system through Mathematical Modeling!

OUTREACH

Our team conduct several activities for further recognition of synthetic biology!

SAFETY

The project is considered to have the minimal risks!

TEAM

Members in USTC_China enjoy themselves this summer!

WELCOME!

Bacteriophage is one of the most severe threats the fermentation factories have to face. To help solve the problem, we design a gene circuit which can both detect and defend against the phages. We use the modified promoter pRM to sense the phage’s infection and initiate the defence. The lysis gene which can make bacteria lyse is installed in our circuit. When it works, the phage won’t be able to take advantage of its host to replicate any longer. To win more time for lysis to function well, we design antisense RNA to prevent the phage from turning into lytic life cycle. Thus, when the lysis protein kills the host, the phage is still at lysogenic life cycle or the newly assembled phages are still immature. By using the quorum sensing system, the bacteria around the host will prepare to defend in advance. Attribute to these parts, our bacteria survive.

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