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From 2012.igem.org

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Contents 1 Gal1 Promoter 1.1 Model Specification 1.1.1 Model Equations 1.1.2 Parameters 1.1.3 Data 1.2 Profile Likelihood 1.3 Markov Analysis 1.3.1 Joint Distribution 1.3.2 Credibility Intervals 1.4 Sensitivity Analysis 1.5 Reference

Gal1 Promoter

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Model Specification

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Model Equations

We used a two species approach for mRNA and Protein concentrations. x_1 and x_2 represent the mRNA and protein levels for the induced promoter and x_3 and x_4 the respective levels for the uninduced promoter.

As no analysis was done with several galactose concentrations hence the hill function that normally models the response to the concentration was replaced by a single factor to improve identifiability.

Parameters

Data

Profile Likelihood

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Markov Analysis

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Joint Distribution

Credibility Intervals

Sensitivity Analysis

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Reference