Team:TU Munich/Modeling/Gal1 Promoter
From 2012.igem.org
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== Model Specification == | == Model Specification == | ||
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[[File:TUM12_Galpromeq.jpg|||right|]] | [[File:TUM12_Galpromeq.jpg|||right|]] | ||
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+ | === Model Equations === | ||
We used a two species approach for mRNA and Protein concentrations. x_1 and x_2 represent the mRNA and protein levels for the induced promoter and x_3 and x_4 the respective levels for the uninduced promoter. | We used a two species approach for mRNA and Protein concentrations. x_1 and x_2 represent the mRNA and protein levels for the induced promoter and x_3 and x_4 the respective levels for the uninduced promoter. |
Revision as of 14:39, 11 September 2012
Contents |
Gal1 Promoter
Model Specification
Model Equations
We used a two species approach for mRNA and Protein concentrations. x_1 and x_2 represent the mRNA and protein levels for the induced promoter and x_3 and x_4 the respective levels for the uninduced promoter.
As no analysis was done with several galactose concentrations hence the hill function that normally models the response to the concentration was replaced by a single factor to improve identifiability.
Parameters
Data
Profile Likelihood
Markov Analysis
Joint Distribution
Credibility Intervals
Sensitivity Analysis