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Team:Evry/Project
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We will bring Xenopus, a model organism in developmental biology, to iGEM for the first time. We hope to show it can be a great multicellular chassis for the iGEM community. We will <FONT COLOR="#FFA500">'''create tools for the next generation of iGEMers'''</FONT> to be able to easily express synthetic systems in various tissues. In order to link all these parts together, we want to create an '''orthogonal, synthetic hormonal system''' using the plant hormone auxin, in order for the different tissues to communicate with one another.</p> | We will bring Xenopus, a model organism in developmental biology, to iGEM for the first time. We hope to show it can be a great multicellular chassis for the iGEM community. We will <FONT COLOR="#FFA500">'''create tools for the next generation of iGEMers'''</FONT> to be able to easily express synthetic systems in various tissues. In order to link all these parts together, we want to create an '''orthogonal, synthetic hormonal system''' using the plant hormone auxin, in order for the different tissues to communicate with one another.</p> | ||
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<h3 style="text-align: center; padding-top:10px;">Our project is composed of these 5 components:</h3> | <h3 style="text-align: center; padding-top:10px;">Our project is composed of these 5 components:</h3> | ||
Revision as of 14:39, 10 July 2012
Project overview
For our first participation in iGEM, we have decided to combine the future and the past, tradition with modernity and our project aims to combine Synthetic biology and the roots of french society: frogs. We will bring Xenopus, a model organism in developmental biology, to iGEM for the first time. We hope to show it can be a great multicellular chassis for the iGEM community. We will create tools for the next generation of iGEMers to be able to easily express synthetic systems in various tissues. In order to link all these parts together, we want to create an orthogonal, synthetic hormonal system using the plant hormone auxin, in order for the different tissues to communicate with one another.
A quick summary of each project is proposed in this page. Please go on the specific page of each project for more details!
The French Froggies: Engineering a new hormonal system in tadpoles
Our aim is making the genetic engineering of synthetic systems in both species of Xenopus (Xenopus laevis and Xenopus tropicalis) that are frogs of African origin. Both species are frequently used in biological research as models amphibians to study the development or toxicology.
The Xenopus is used as a "biosensor" allowing more meaningful measures of the dangers to humans than could be obtained with unicellular organisms. Furthermore, the use of a multicellular organism provides an additional level of complexity compared to single-celled organisms which multiplies the potential applications in terms of synthetic biology.
Go and visit the project page >
Modeling a tadpole: a multi-level approach
Go and visit the project page >
Biotic games: Better undersanding of tadpole behavior through gaming
Go and visit the project page >
Cloning: A new revolution in iGEM cloning
Go and visit the project page >
