Team:Evry/Achievements

From 2012.igem.org

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<li>We brought a new multicellular <a href="http://2012.igem.org/Team:Evry/FrenchFrog">chassis</a> to iGEM</li>
<li>We brought a new multicellular <a href="http://2012.igem.org/Team:Evry/FrenchFrog">chassis</a> to iGEM</li>
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<li>We submitted <a href="http://2012.igem.org/Team:Evry/Parts">28 biobricks</a> to the registry, including the first working Xenopus biobricks</li>
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<li>We submitted <a href="http://2012.igem.org/Team:Evry/Parts">21 biobricks</a> to the registry, including the first working Xenopus biobricks</li>
<li>We characterized 12 Biobricks:
<li>We characterized 12 Biobricks:
<a href="http://partsregistry.org/wiki/index.php?title=Part:BBa_K812000">BBa_K812000</a>,
<a href="http://partsregistry.org/wiki/index.php?title=Part:BBa_K812000">BBa_K812000</a>,
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<li>We designed a method for testing multicellular systems in <a href="http://2012.igem.org/Team:Evry/FrenchFrog"><i>Xenopus</i></a> rapidly</li>
<li>We designed a method for testing multicellular systems in <a href="http://2012.igem.org/Team:Evry/FrenchFrog"><i>Xenopus</i></a> rapidly</li>
<li>We provided 3 new plasmids for using this method, which include debugging tools, <a href="http://partsregistry.org/wiki/index.php?title=Part:BBa_K812000">BBa_K812000</a>, <a href="http://partsregistry.org/wiki/index.php?title=Part:BBa_K812200">BBa_K812200</a>, <a href="http://partsregistry.org/wiki/index.php?title=Part:BBa_K812300">BBa_K812300</a></li>
<li>We provided 3 new plasmids for using this method, which include debugging tools, <a href="http://partsregistry.org/wiki/index.php?title=Part:BBa_K812000">BBa_K812000</a>, <a href="http://partsregistry.org/wiki/index.php?title=Part:BBa_K812200">BBa_K812200</a>, <a href="http://partsregistry.org/wiki/index.php?title=Part:BBa_K812300">BBa_K812300</a></li>
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<li>Our reporters and promoters weere <a href="http://2012.igem.org/Team:Evry/Tadpole_injection1">characterized</a>.</li>
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<li>Our reporters and promoters were <a href="http://2012.igem.org/Team:Evry/Tadpole_injection1">characterized</a>.</li>
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<li>We did a collaboration with Team Slovenia and we injected their construction into our fertilized embryos: <a href="http://2012.igem.org/Team:Evry/TeamSlovenia_collaboration">Results</a></li>
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<li>We designed a new <a href="http://2012.igem.org/Team:Evry/GB">biobrick standard</a which allows one-shot coding device assembly, while still being compatible with the RFC10 standard</li>
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<li>We designed a new <a href="http://2012.igem.org/Team:Evry/GB#requirement">biobrick standard</a which allows one-shot coding device assembly, while still being compatible with the RFC10 standard</li>
<li>We demonstrated it <a href="http://2012.igem.org/Team:Evry/GB#GB">works</a> (still with a low efficiency) and that the protocol have to be further optimized</li>
<li>We demonstrated it <a href="http://2012.igem.org/Team:Evry/GB#GB">works</a> (still with a low efficiency) and that the protocol have to be further optimized</li>
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<li>We managed to assemble parts with a very high efficiency using Golden Gate and the GoldenBricks plasmids</li>
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<li>We <a href="http://2012.igem.org/Team:Evry/GB#GG">managed</a> to assemble parts with a very high efficiency using Golden Gate and the GoldenBricks plasmids</li>
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</ul>
<center><h2><a href="http://2012.igem.org/Team:Evry/Modeling"><img src="http://2012.igem.org/wiki/images/5/5b/ModelingDHIUHEIUHD.png" width="200px"></a></h2></center>
<center><h2><a href="http://2012.igem.org/Team:Evry/Modeling"><img src="http://2012.igem.org/wiki/images/5/5b/ModelingDHIUHEIUHD.png" width="200px"></a></h2></center>
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<ul>
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<li>We used a multi-level approach to approach a physiological system with a general integrative model in which we plugged data from more detailed models</li>
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<li>We used a <a href="http://2012.igem.org/Team:Evry/Modeling">multi-level approach</a> to model various aspects of the <a href="http://2012.igem.org/Team:Evry/Auxin_diffusion">physiology</a> and <a href="http://2012.igem.org/Team:Evry/auxin_production">cellular behaviour</a> of Xenopus.</li>
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<li>We sucessfully used Ordinary differential equations, partial differential equations and Guillespie Montecarlo algorithm to model detailed system in the tadpole</li>
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<li>All our models <a href="http://2012.igem.org/Team:Evry/model_integration">fit together</a> to comprehensively depict all the processes from the experimental protocol to <a href="http://2012.igem.org/Team:Evry/auxin_detection">reporter expression</a></li>
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<li>We used many modelisation techniques (<a href="http://2012.igem.org/Team:Evry/ODE_model">Ordinary differential equations</a>, <a href="http://2012.igem.org/Team:Evry/auxin_pde">some derived</a> from partial differential equations and <a href="http://2012.igem.org/Team:Evry/plasmid_splitting">Gillespie algorithm</a>) in order to benefit from their respective strength.</li>
</ul>
</ul>
<center><h2><a href="http://2012.igem.org/Team:Evry/HumanPractice"><img src="http://2012.igem.org/wiki/images/b/ba/HumanPractice.png" width="200px"></a></h2></center>
<center><h2><a href="http://2012.igem.org/Team:Evry/HumanPractice"><img src="http://2012.igem.org/wiki/images/b/ba/HumanPractice.png" width="200px"></a></h2></center>
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<ul>
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<li>We submitted an extensive report of our conclusions about synthetic biology in vertebrates, which is the fruit of our long reflection we conducted over the summer.</li>
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<li>We submitted an <a href="http://2012.igem.org/Team:Evry/HumanPractice">extensive report</a> of our conclusions about synthetic biology in vertebrates, which is the fruit of our long reflection we conducted over the summer.</li>
</ul>
</ul>

Latest revision as of 03:24, 27 October 2012

iGEM Evry 2012 achievements


Asides from having lots of fun, meeting great people, gathering around cheese and wine and lazying around the Genopole gardens during lunch break, we also did a little bit of work. Here is a list of our achievements:



  • We designed a multicellular hormonal system
  • We created an Auxin production (BBa_K812014) device for use in eukaryotes from the prokaryote one
  • We submitted the Tir1 (BBa_K812012) auxin detection device to the registry
  • We showed the first Synthetic ecosystem, with a unicellular chassis (E.coli) improved inside a multicellular chassis (Xenopus)

  • We designed a new biobrick standard
  • We demonstrated it works (still with a low efficiency) and that the protocol have to be further optimized
  • We managed to assemble parts with a very high efficiency using Golden Gate and the GoldenBricks plasmids

  • We submitted an extensive report of our conclusions about synthetic biology in vertebrates, which is the fruit of our long reflection we conducted over the summer.