Team:Edinburgh/Modelling/Biosensors/

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The aim is to model a growth-based biosensor and compare it with a model of a conventional non-growth based biosensor, which generally outputs GFP expression in response to an inducer.
The aim is to model a growth-based biosensor and compare it with a model of a conventional non-growth based biosensor, which generally outputs GFP expression in response to an inducer.
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The growth-based biosensor will instead have as an output the expression of a gene which facilitates the availability of a substrate and thus increasing the growth rate of the organism. A candidate gene is sucrose hydrolase, which enables E. coli K12 to use sucrose as a carbon source.
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The growth-based biosensor will instead have as an output the expression of a gene which facilitates the availability of a substrate and thus increasing the growth rate of the organism. A candidate gene is sucrose hydrolase, which enables <i>E. coli</i> K12 to use sucrose as a carbon source.
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Revision as of 00:08, 27 September 2012

Growth-based Biosensor

Objective:

The aim is to model a growth-based biosensor and compare it with a model of a conventional non-growth based biosensor, which generally outputs GFP expression in response to an inducer. The growth-based biosensor will instead have as an output the expression of a gene which facilitates the availability of a substrate and thus increasing the growth rate of the organism. A candidate gene is sucrose hydrolase, which enables E. coli K12 to use sucrose as a carbon source.

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