Team:SUSTC-Shenzhen-B/algorithm
From 2012.igem.org
Overview of Our Algorithm
Our team created a pc software and an online tool to help users calculate the efficiency of their terminators.
To calculate the efficiency of terminator efficiency, there are three steps.
First,we cut the input terminator sequence into three parts, including A tail, stemloop, T tail using Carleton L Kingsford Scoring System (Scoring System 1).
Next, we score the terminator based on the d'Aubenton Carafa Scoring System(Scoring System 2) or Elena A Lesnik Scoring System(Scoring System 3).
Finally, we calculate the efficiency of terminator using the simulation formular created by our team.
From the picture below we can see that there are two choices when scoring terminators. So there are two algorithms of our software.