Team:EPF-Lausanne/Modeling

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= Introduction =
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[[Team:EPF-Lausanne/Modeling/lovtap|LovTAP]]
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== How LovTAP is thought to work ==
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=== Allosteric regulation ===
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In a protein, generally an enzyme, an allosteric site is any part of the protein other than the active site.
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Allosteric regulation of a protein consists in modifying its properties by interacting with an allosteric site.
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One example would be the regulation in the tryptophan (trp) operon,
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a group of genes studied in E. coli that are required for the synthesis of the amino acid tryptophan.
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The expression of these genes can be blocked by the homodimeric protein tryptophan repressor
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(TrpR), by binding the operator of the operon. TrpR repressing function is only active when
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tryptophan is bound to its allosteric sites, i.e. it blocks the production of tryptophan when the
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concentration of tryptophan is high.
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Revision as of 13:51, 26 July 2012

LovTAP