From 2012.igem.org
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| <h2>Project</h2> | | <h2>Project</h2> |
- | <p> Visit our <a href="https://2012.igem.org/Team:Evry/Project">project</a> to get a first taste of what we are working on. </p> | + | |
| + | Building on a long-standing French fascination for frogs, we wanted to spread this enthusiasm to the world of synthetic biology by introducing a new, vertebrate chassis to the community: Xenopus tropicalis. This leap towards multicellular biological engineering required new tools, so we first developed a new set of frog compatible vectors, biobricked tissue specific promoters and a new technique to assemble them in a single shot. To benefit from tissue compartmentalisation, we created a synthetic, orthogonal hormonal system using the plant molecule auxin. We also investigated E. coli/Xenopus interfacing, effectively creating a synthetic ecosystem. We modelled our system at the organism scale, using a multi-level and multi-technique approach. Finally, working with whole animals during iGEM brought a load of difficult ethical questions regarding animal biotechnologies and experimentation. This led us to wonder: Are we a chassis? |
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| + | <p> Visit our <a href="https://2012.igem.org/Team:Evry/Project">project</a> to understand deeper what we are working on. </p> |
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Revision as of 09:19, 8 September 2012