Team:Tianjin
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Orthogonal ribosomes (o-ribosomes)are able to selectively translate mRNA, with altered Shine-Dalgarno (SD) sequence, not recognized by host ribosomes. Therefore, we are able to use this powerful tools to investigate translational regulation. This year, we use the o-ribosome to examine the regulation of existing protein synthesis network by rationally designing o-SD sequence, hoping to somewhat increase the yield of the protein. In addition, it is possible to construct a logical gate structure using the o-ribosome to demonstrate the beauty of the complex synthesis network. | |
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TJU iGEM 2012