Team:Slovenia/ModelingMutualRepressorSwitch
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Revision as of 20:04, 25 September 2012
Modeling - mutual repressor switch
- Deterministic model
- Stochastic model
- C#Sim model
Deterministic model of the mutual repressor switch
Deterministic analysis demonstrated that while theoretical conditions under which the mutual repressor switch would exhibit bistability exist, they are unlikely to occur in a realistic experimental setting. This was because:
Increase in cooperativity lead to more robust behavior – higher expression levels of stable states were reached and higher – but still low - tolerance to leaky expression was observed. Experimental results confirmed that the mutual repressor switch did not exhibit bistability. |