Team:ETH Zurich/HumanPractice/NRP59

From 2012.igem.org

(Difference between revisions)
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=== Research Topics ===
=== Research Topics ===
-
The national research program on genetically modified plants focused on many interdisciplinary areas. The research evaluated the relationship between plant biotechnology and environment by looking closer at the impact of resistancies in economic plants, biodiversity and the transfer of genes from GMP to wild type plants. Another focus were political, social and economic aspects that included the role of the media for the formation of the public opinion. Another dealt with the evaluation and management of risks of GMP.  
+
The national research program on genetically modified plants focused on many interdisciplinary areas. The research evaluated the relationship between plant biotechnology and environment by looking closer at the impact of resistancies in economic plants, biodiversity and the transfer of genes from GMP to wild type plants. Another focus were political, social and economic aspects that included the role of the media for the formation of the public opinion. Another dealt with the evaluation and management of risks of GMP. <br \>
-
While 5 years are too short to conduct a long term study, the last part was to review published studies on medical issues of GMPs relevant for Switzerland, various aspects of coexistence of natural plants and GMP in crop production and a synthesis of studies on biological issues of GMPs.
+
While 5 years are too short to conduct a long term study, the last part was to review published studies on medical issues of GMPs relevant for Switzerland, various aspects of coexistence of natural plants and GMP in crop production and a synthesis of studies on biological issues of GMPs. <br \>
-
Interestingly, throughout the whole project, focus lied also on the communication of the results to the Swiss public and to the politicians.  
+
Interestingly, throughout the whole project, focus lied also on the communication of the results to the Swiss public and to the politicians.   <br \>
=== Background ===
=== Background ===
-
Worldwide, the use of GMP is very common: 29 countries, 19 of which emerging or developing countries, use mostly maize, soy, cotton and sugarcane which is genetically modified. With research on other plants, the worldwide use of GMPs is assumed to grow within the next years.
+
Worldwide, the use of GMP is very common: 29 countries, 19 of which emerging or developing countries, use mostly maize, soy, cotton and sugarcane which is genetically modified. With research on other plants, the worldwide use of GMPs is assumed to grow within the next years. <br \>
-
In Europe, over 40 different GMPs are allowed to be used in food for both human and animal. Never the less, the cultivation of GMP is allowed for only two species: maize and starch rich potatoes. Most research was outsourced to other countries for two main reasons: the cost of outdoor experiments and the critical atmospheres towards GMPs. As a paradox, the high demands on safety led to the fact that only a few companies can afford research in GMPs which leads to an undesired monopolization of the field of commercially used GMPs. Being established 15 years ago; green plant biotechnology is still considered a very modern technology in the public opinion!  
+
In Europe, over 40 different GMPs are allowed to be used in food for both human and animal. Never the less, the cultivation of GMP is allowed for only two species: maize and starch rich potatoes. Most research was outsourced to other countries for two main reasons: the cost of outdoor experiments and the critical atmospheres towards GMPs. As a paradox, the high demands on safety led to the fact that only a few companies can afford research in GMPs which leads to an undesired monopolization of the field of commercially used GMPs. Being established 15 years ago; green plant biotechnology is still considered a very modern technology in the public opinion!   <br \>
-
Agriculture in Swiss needs to become more efficient, sustainable and ecologically, preferably without an increase of cost, to meet futures demand for food and at the same time maintain a sound environment. GMPs can help to protect nature and environment that can be harmed through extensive agriculture by lowering the use of herbicide and prevent crop failure.  
+
Agriculture in Swiss needs to become more efficient, sustainable and ecologically, preferably without an increase of cost, to meet futures demand for food and at the same time maintain a sound environment. GMPs can help to protect nature and environment that can be harmed through extensive agriculture by lowering the use of herbicide and prevent crop failure. <br \>
=== Results ===
=== Results ===
-
The results of 5 years of work in 30 projects worth an investment of 12 million Swiss francs (ca. 13 million US dollars) of NFP 59 were published on August 28th and a 300 pages long book was published online on September 11th in German and French and later, on September 21st in English.
+
The results of 5 years of work in 30 projects worth an investment of 12 million Swiss francs (ca. 13 million US dollars) of NFP 59 were published on August 28th and a 300 pages long book was published online on September 11th in German and French and later, on September 21st in English. <br \>
-
The results of the NRP stated that there is no or very little risk of GMP for health and environment. At the same time, specifically for Switzerland, the benefit of using GMPs is low as well given today’s circumstances. Never the less, with new breakthroughs in research, the benefit of GMPs could increase, making them more attractive for Switzerland. From the analysis of over thousand studies from worldwide research about GMPs, no risks could be concluded. Any problems that occurred are not caused by GMPs but arise from bad agricultural practice such as extensive monoculture. The same result is found by the 11 projects of the NRP that dealt with environmental risks of genetically modified strawberry, potato and wheat: neither soil fertility nor microbes or useful insects were harmed by planting GMPs.  
+
The results of the NRP stated that there is no or very little risk of GMP for health and environment. At the same time, specifically for Switzerland, the benefit of using GMPs is low as well given today’s circumstances. Never the less, with new breakthroughs in research, the benefit of GMPs could increase, making them more attractive for Switzerland. From the analysis of over thousand studies from worldwide research about GMPs, no risks could be concluded. Any problems that occurred are not caused by GMPs but arise from bad agricultural practice such as extensive monoculture. The same result is found by the 11 projects of the NRP that dealt with environmental risks of genetically modified strawberry, potato and wheat: neither soil fertility nor microbes or useful insects were harmed by planting GMPs.   <br \>
-
From a social perspective, 80% of the Swiss like to have the choice between gene-technique-free food and genetically engineered food which would be bought by 25 % of the Swiss. NRP proposes that the coexistence of genetically modified and non modified plants could be established in Switzerland with ‘zones’ of cultivation. Being a small country in the beautiful Alps, Switzerland has at the moment many small sites where crops can be planted, compared to bigger countries that can have much larger fields. The findings of NRP specifically evaluate the Swiss situation.
+
From a social perspective, 80% of the Swiss like to have the choice between gene-technique-free food and genetically engineered food which would be bought by 25 % of the Swiss. NRP proposes that the coexistence of genetically modified and non modified plants could be established in Switzerland with ‘zones’ of cultivation. Being a small country in the beautiful Alps, Switzerland has at the moment many small sites where crops can be planted, compared to bigger countries that can have much larger fields. The findings of NRP specifically evaluate the Swiss situation. <br \>
-
It was pointed out that outdoor research is necessary to evaluate the potential of GMP, since the behavior in controlled greenhouse environment might differ from the behavior in real nature, to good and to bad account.
+
It was pointed out that outdoor research is necessary to evaluate the potential of GMP, since the behavior in controlled greenhouse environment might differ from the behavior in real nature, to good and to bad account.   <br \>
=== Reactions ===  
=== Reactions ===  
-
In March 2010, a preliminary report stated that there is no off target effect observed for mildew resistant wheat. Neither plant louses nor other insects like flies that are domestic in Switzerland showed a different effect when fed with wild type or genetically manipulated wheat. Later, it was found out that even though wheat is resistant to mildew and showed a higher yield in the greenhouse, it performed less well in the outdoor tests. Even worse, it was more susceptible for the dangerous ergot fungi which are highly poisonous. Though the explanation from Simon Zeller, a PhD student who worked on the outdoor test, does not shine a good light on gene technology: he argues that the mildew resistance puts some pressure on the fertility of male wheat plants and subsequently it takes longer to fertilize the female plants. This gives ergot more time to infect the plants. This turn of events was hard to foresee and needed the outdoor research, as Simon Zeller states in the article. Other voices, like Dirk Dobbelaere, Professor for Cell Biology of University of Bern,  call it ''‘trivial’'' that there are different results in green houses and outdoor tests and that the problem of ergot is ''‘hundreds of years old’''. The NRP 59 is rather undifferentiated in the wrap up of the results on the outdoor research on wheat, even though the outdoor research was a big part of the whole research. Contrariwise, NRP 59 points out the research of the literature studies. Urs Niggli, director of the Research institute of organic agriculture, said: ''‘There was a need to point out that gene technology is good’'' while at the same time damp results from his own institute: ''‘we found no risks of GMPs, but we did not work with the newest strains available’''.  
+
In March 2010, a preliminary report stated that there is no off target effect observed for mildew resistant wheat. Neither plant louses nor other insects like flies that are domestic in Switzerland showed a different effect when fed with wild type or genetically manipulated wheat. Later, it was found out that even though wheat is resistant to mildew and showed a higher yield in the greenhouse, it performed less well in the outdoor tests. Even worse, it was more susceptible for the dangerous ergot fungi which are highly poisonous. Though the explanation from Simon Zeller, a PhD student who worked on the outdoor test, does not shine a good light on gene technology: he argues that the mildew resistance puts some pressure on the fertility of male wheat plants and subsequently it takes longer to fertilize the female plants. This gives ergot more time to infect the plants. This turn of events was hard to foresee and needed the outdoor research, as Simon Zeller states in the article. Other voices, like Dirk Dobbelaere, Professor for Cell Biology of University of Bern,  call it ''‘trivial’'' that there are different results in green houses and outdoor tests and that the problem of ergot is ''‘hundreds of years old’''. The NRP 59 is rather undifferentiated in the wrap up of the results on the outdoor research on wheat, even though the outdoor research was a big part of the whole research. Contrariwise, NRP 59 points out the research of the literature studies. Urs Niggli, director of the Research institute of organic agriculture, said: ''‘There was a need to point out that gene technology is good’'' while at the same time damp results from his own institute: ''‘we found no risks of GMPs, but we did not work with the newest strains available’''.   <br \>
-
In October 2010, the newspaper ‘Sonntagszeitung’ already titled: ''‘green gene technology about to fold’'', since the cost for outdoor experiments exploded. Militant opponents of green gene technology destroyed the fields of the outdoor tests of GMPs. Thus, the costs to guarantee the safety of the fields were about as high as the costs for the experiments (0,78 CHF for safety for 1 CHF that was spend on research!). The fields needed to be guarded day and night and completely fenced, so the national research council had to provide more money for the outdoor research. After the end of the three year project, it is not yet decided what happens to the fenced research facility, which operation costs about 750 000 CHF a year. On the one hand, the facility can provide know how and technology for the research with GMPs, on the other hand it is not known if further experiments will be done in Switzerland if the moratorium on commercially used plants is extended further and further.  
+
In October 2010, the newspaper ‘Sonntagszeitung’ already titled: ''‘green gene technology about to fold’'', since the cost for outdoor experiments exploded. Militant opponents of green gene technology destroyed the fields of the outdoor tests of GMPs. Thus, the costs to guarantee the safety of the fields were about as high as the costs for the experiments (0,78 CHF for safety for 1 CHF that was spend on research!). The fields needed to be guarded day and night and completely fenced, so the national research council had to provide more money for the outdoor research. After the end of the three year project, it is not yet decided what happens to the fenced research facility, which operation costs about 750 000 CHF a year. On the one hand, the facility can provide know how and technology for the research with GMPs, on the other hand it is not known if further experiments will be done in Switzerland if the moratorium on commercially used plants is extended further and further.   <br \>
-
In a way, that was a victory for the opponents of GMP, as illustrated by the quote by Dieter Imboden, president of the National Research Council of the Swiss National funds: '' 'I do not think that there will be more outdoor tests in Switzerland' ''.  Yet outdoor experiments are important since the result from green houses can be reverted in outdoor experiments or the positive effects can be lower in a less controlled environment such as nature. Without a testing infrastructure the tests are way too expensive. A similar argument can be found in the interview with Prof. Potrykus, who states:” The series of moratoriums decisively contributed to the fact that research with GMP makes no more sense in Switzerland, with all consequences. Switzerland bows out of the development of a technology that is regarded as '' ‘strategic future technology’ in many other countries. Switzerland once had a leading position on this field (see golden rice project)' '', when asked for the consequences of the moratorium. About the consequences, he thinks '' ‘One must let the Swiss carry the can of their decision. They will realize when it is too late […]’ '' . Mr Markus Ritter says on the topic: '' ‘. My position there is to keep the research safe and wait for the breakthrough. Cultivation experiments however, the ones that are prohibited, should be done in big agricultural states not here in Switzerland. But the research is important and we want to preserve it.’ ''.  
+
In a way, that was a victory for the opponents of GMP, as illustrated by the quote by Dieter Imboden, president of the National Research Council of the Swiss National funds: '' 'I do not think that there will be more outdoor tests in Switzerland' ''.  Yet outdoor experiments are important since the result from green houses can be reverted in outdoor experiments or the positive effects can be lower in a less controlled environment such as nature. Without a testing infrastructure the tests are way too expensive. A similar argument can be found in the interview with Prof. Potrykus, who states:” The series of moratoriums decisively contributed to the fact that research with GMP makes no more sense in Switzerland, with all consequences. Switzerland bows out of the development of a technology that is regarded as '' ‘strategic future technology’ in many other countries. Switzerland once had a leading position on this field (see golden rice project)' '', when asked for the consequences of the moratorium. About the consequences, he thinks '' ‘One must let the Swiss carry the can of their decision. They will realize when it is too late […]’ '' . Mr Markus Ritter says on the topic: '' ‘. My position there is to keep the research safe and wait for the breakthrough. Cultivation experiments however, the ones that are prohibited, should be done in big agricultural states not here in Switzerland. But the research is important and we want to preserve it.’ ''.   <br \>
-
He gives another reason to preserve the research in this technology : ‘We are currently running towards many big challenges, like climate change und increasing population. We may in the future be in need of plants that can grow in dry conditions.’
+
He gives another reason to preserve the research in this technology : '' ‘We are currently running towards many big challenges, like climate change und increasing population. We may in the future be in need of plants that can grow in dry conditions.’ '' <br \>
-
As a response on the final results, the article'' ‘science has spoken’ '' was published in ''‘Wochenzeitung’ ''. It quotes again Dieter Imboden who warns: '' “programs as NRP 59 raises the expectation that science can decide about such polarizing questions. Science cannot render such help” ''. Even though '' ‘science’ '' gave a positive answer as a result of NRP, this does not mean there is all of a sudden great acceptance for a technology that raises many fears and doubts in population. Furthermore, scientists do not all agree to the estimated costs and benefits of GMPs, so there is a lot of room for discussion left. Despite of the fact that disagreement is an integral part of research and almost a prerequisite of progress, the dispute about the findings of NRP 59 are not helpful in gaining the populations trust in research results. Even worse, some researchers where confronted with reproaches of belonging to gene technology friendly organizations and therefore be biased. Scientists seemed to be careful since whatever they say may be used as a slightly out of context argument by any site of the discussion. These examples show that the polarization of the public into black and white thinking also reflects on scientists. Prof. Potrykus stated that '' ‘it is also the medias fault’ '' that there are '' ‘a few that are scientifically well informed, but the majority feels ensured in their fears and prejudices because of the continued moratorium. ‘ ''
+
As a response on the final results, the article'' ‘science has spoken’ '' was published in ''‘Wochenzeitung’ ''. It quotes again Dieter Imboden who warns: '' “programs as NRP 59 raises the expectation that science can decide about such polarizing questions. Science cannot render such help” ''. Even though '' ‘science’ '' gave a positive answer as a result of NRP, this does not mean there is all of a sudden great acceptance for a technology that raises many fears and doubts in population. Furthermore, scientists do not all agree to the estimated costs and benefits of GMPs, so there is a lot of room for discussion left. Despite of the fact that disagreement is an integral part of research and almost a prerequisite of progress, the dispute about the findings of NRP 59 are not helpful in gaining the populations trust in research results. Even worse, some researchers where confronted with reproaches of belonging to gene technology friendly organizations and therefore be biased. Scientists seemed to be careful since whatever they say may be used as a slightly out of context argument by any site of the discussion. These examples show that the polarization of the public into black and white thinking also reflects on scientists. Prof. Potrykus stated that '' ‘it is also the medias fault’ '' that there are '' ‘a few that are scientifically well informed, but the majority feels ensured in their fears and prejudices because of the continued moratorium. ‘ '' <br \>
National Council Markus Ritter argues in a different way as an answer to the question if people are not well informed: '' ‘The more we are proceeding into the direction of globalization and a highly technological world, the more people want untouched nature, culture and values, and thy try to at least protect their food as an untouched refugium. The say: “No! Everything, but not our food!”‘ '' . Despite Mr. Ritter sees the '' ‘large potential’ of GMPs, ‘we now have no hunger in Switzerland; nobody in this country knows the problem of hunger. So the potential is found more in the Third World.’ '' That explains the answer of Prof. Potrykus, who answers '' ‘The people that face the danger of their children becoming blind or die due to the lack of vitamin A have no problem with GMPs yet. Never the less Greenpeace etc. work intensively towards changing this fact.’ '' when being asked: '' ‘Can the higher acceptance of golden rice in the population of poor countries be explained by the fact that the use of GMP is better communicated? Are the people in those countries informed well enough?’'' .  
National Council Markus Ritter argues in a different way as an answer to the question if people are not well informed: '' ‘The more we are proceeding into the direction of globalization and a highly technological world, the more people want untouched nature, culture and values, and thy try to at least protect their food as an untouched refugium. The say: “No! Everything, but not our food!”‘ '' . Despite Mr. Ritter sees the '' ‘large potential’ of GMPs, ‘we now have no hunger in Switzerland; nobody in this country knows the problem of hunger. So the potential is found more in the Third World.’ '' That explains the answer of Prof. Potrykus, who answers '' ‘The people that face the danger of their children becoming blind or die due to the lack of vitamin A have no problem with GMPs yet. Never the less Greenpeace etc. work intensively towards changing this fact.’ '' when being asked: '' ‘Can the higher acceptance of golden rice in the population of poor countries be explained by the fact that the use of GMP is better communicated? Are the people in those countries informed well enough?’'' .  
   
   
=== Opinion ===
=== Opinion ===
-
To conclude this little excursion into the Swiss genetically modified plant landscape, I want to give my own personal opinion on the topic: With myself having a strong interest in biology, research and technology, of course my view was biased towards the ‘pro’ GMP side. I hope I could block out the bias and give a neutral review of the situation. In addition, I must admit I could also find some prejudices in myself and I could use the opportunity of digging into some material and writing this text to lower or to get rid of them.  
+
To conclude this little excursion into the Swiss genetically modified plant landscape, I want to give my own personal opinion on the topic: With myself having a strong interest in biology, research and technology, of course my view was biased towards the ‘pro’ GMP side. I hope I could block out the bias and give a neutral review of the situation. In addition, I must admit I could also find some prejudices in myself and I could use the opportunity of digging into some material and writing this text to lower or to get rid of them.   <br \>
-
To sum it up, the subject of GMPs is nothing science alone can clearly answer. Many social factors need to be considered before deciding what might be right, wrong or best and where it can be used. The matter is not white or black but comes in many shades. The only thing I know for myself is that one should try everything to keep the research in this field up, since it can have many positive outcomes for society, even if it is, for many reasons, at the moment not yet ready to be fully established in society.  
+
To sum it up, the subject of GMPs is nothing science alone can clearly answer. Many social factors need to be considered before deciding what might be right, wrong or best and where it can be used. The matter is not white or black but comes in many shades. The only thing I know for myself is that one should try everything to keep the research in this field up, since it can have many positive outcomes for society, even if it is, for many reasons, at the moment not yet ready to be fully established in society. <br \>
=== References ===
=== References ===
-
http://www.nfp59.ch/d_index.cfm
+
http://www.nfp59.ch/d_index.cfm <br \>
(*) Peter, M., Lindfeld, A. and Nentwig, W. (2010): Does GM
(*) Peter, M., Lindfeld, A. and Nentwig, W. (2010): Does GM
wheat affect saprophagous Diptera species (Drosophilidae,
wheat affect saprophagous Diptera species (Drosophilidae,
Phoridae)? Pedobiologia, doi: 10.1016/j.pedo.2009.12.006 (als
Phoridae)? Pedobiologia, doi: 10.1016/j.pedo.2009.12.006 (als
-
PDF beim SNF erhältlich; E-Mail: pri@snf.ch)
+
PDF beim SNF erhältlich; E-Mail: pri@snf.ch) <br \>
(**) von Burg, S., Müller, C. B. and Romeis, J. (2010): Transgenic
(**) von Burg, S., Müller, C. B. and Romeis, J. (2010): Transgenic
disease-resistant wheat does not affect the clonal performance
disease-resistant wheat does not affect the clonal performance
of the aphid Metolophium dirhodum Walker. Basic
of the aphid Metolophium dirhodum Walker. Basic
-
and Applied Ecology, doi: 10.1016/j.baae.2010.02.003 (als PDF beim SNF erhältlich; E-Mail: pri@snf.ch)
+
and Applied Ecology, doi: 10.1016/j.baae.2010.02.003 (als PDF beim SNF erhältlich; E-Mail: pri@snf.ch) <br \>
-
http://www.sonntagszeitung.ch/wissen/artikel-detailseite/?newsid=153963
+
http://www.sonntagszeitung.ch/wissen/artikel-detailseite/?newsid=153963 <br \>
-
http://www.woz.ch/1236/gentech-moratorium/die-wissenschaft-hat-gesprochen
+
http://www.woz.ch/1236/gentech-moratorium/die-wissenschaft-hat-gesprochen <br \>
{{:Team:ETH_Zurich/Templates/Footer}}
{{:Team:ETH_Zurich/Templates/Footer}}

Revision as of 20:22, 26 September 2012

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Contents

NRP 59

Introduction

Location of Switzerland in Europe

In 2005, the Swiss decided on a five year Moratorium on the commercial use of GMPs in a referendum with 55.7 % of the voters in favor of the moratorium. At the same time, the government conducted a national research program ([http://www.nfp59.ch NRP]) with the title ‘Benefits and risks of the deliberate release of genetically modified plants’. The aim of the so called NRP 59 was to do research on safety, benefits and risks of GMP regarding specifically the situation and conditions in Switzerland.
In 2010, the moratorium was elongated for three more years until November 2013 to wait for the final results of NRP 59 that should provide a solid scientific basis for a broad public discussion of the topic.
This year, 2012, the NFP 59 published its final results. We want to take the opportunity to let people from other countries know how Switzerland deals with genetically modified plants (GMP). To further critically access the results of NFP 59, we talked to two important players that have an impact on Swiss plant biotechnology: [http://markusritter.ch/ Mr. Markus Ritter] (link in German, French or Italy), member of the Swiss National Council and head of the swiss farmers’ association and [http://www.goldenrice.org/Content1-Who/who_Ingo.php Prof. Ingo Potrykus], who is one of the inventors of '[http://www.goldenrice.org/ golden rice]'. Both were so kind to answer a few of our questions which answers are included in this essay. Read the English translation as well as the German original of the full interview with Prof. Potrykus and Mr. Markus Ritter.

Research Topics

The national research program on genetically modified plants focused on many interdisciplinary areas. The research evaluated the relationship between plant biotechnology and environment by looking closer at the impact of resistancies in economic plants, biodiversity and the transfer of genes from GMP to wild type plants. Another focus were political, social and economic aspects that included the role of the media for the formation of the public opinion. Another dealt with the evaluation and management of risks of GMP.
While 5 years are too short to conduct a long term study, the last part was to review published studies on medical issues of GMPs relevant for Switzerland, various aspects of coexistence of natural plants and GMP in crop production and a synthesis of studies on biological issues of GMPs.
Interestingly, throughout the whole project, focus lied also on the communication of the results to the Swiss public and to the politicians.

Background

Worldwide, the use of GMP is very common: 29 countries, 19 of which emerging or developing countries, use mostly maize, soy, cotton and sugarcane which is genetically modified. With research on other plants, the worldwide use of GMPs is assumed to grow within the next years.
In Europe, over 40 different GMPs are allowed to be used in food for both human and animal. Never the less, the cultivation of GMP is allowed for only two species: maize and starch rich potatoes. Most research was outsourced to other countries for two main reasons: the cost of outdoor experiments and the critical atmospheres towards GMPs. As a paradox, the high demands on safety led to the fact that only a few companies can afford research in GMPs which leads to an undesired monopolization of the field of commercially used GMPs. Being established 15 years ago; green plant biotechnology is still considered a very modern technology in the public opinion!
Agriculture in Swiss needs to become more efficient, sustainable and ecologically, preferably without an increase of cost, to meet futures demand for food and at the same time maintain a sound environment. GMPs can help to protect nature and environment that can be harmed through extensive agriculture by lowering the use of herbicide and prevent crop failure.

Results

The results of 5 years of work in 30 projects worth an investment of 12 million Swiss francs (ca. 13 million US dollars) of NFP 59 were published on August 28th and a 300 pages long book was published online on September 11th in German and French and later, on September 21st in English.
The results of the NRP stated that there is no or very little risk of GMP for health and environment. At the same time, specifically for Switzerland, the benefit of using GMPs is low as well given today’s circumstances. Never the less, with new breakthroughs in research, the benefit of GMPs could increase, making them more attractive for Switzerland. From the analysis of over thousand studies from worldwide research about GMPs, no risks could be concluded. Any problems that occurred are not caused by GMPs but arise from bad agricultural practice such as extensive monoculture. The same result is found by the 11 projects of the NRP that dealt with environmental risks of genetically modified strawberry, potato and wheat: neither soil fertility nor microbes or useful insects were harmed by planting GMPs.
From a social perspective, 80% of the Swiss like to have the choice between gene-technique-free food and genetically engineered food which would be bought by 25 % of the Swiss. NRP proposes that the coexistence of genetically modified and non modified plants could be established in Switzerland with ‘zones’ of cultivation. Being a small country in the beautiful Alps, Switzerland has at the moment many small sites where crops can be planted, compared to bigger countries that can have much larger fields. The findings of NRP specifically evaluate the Swiss situation.
It was pointed out that outdoor research is necessary to evaluate the potential of GMP, since the behavior in controlled greenhouse environment might differ from the behavior in real nature, to good and to bad account.

Reactions

In March 2010, a preliminary report stated that there is no off target effect observed for mildew resistant wheat. Neither plant louses nor other insects like flies that are domestic in Switzerland showed a different effect when fed with wild type or genetically manipulated wheat. Later, it was found out that even though wheat is resistant to mildew and showed a higher yield in the greenhouse, it performed less well in the outdoor tests. Even worse, it was more susceptible for the dangerous ergot fungi which are highly poisonous. Though the explanation from Simon Zeller, a PhD student who worked on the outdoor test, does not shine a good light on gene technology: he argues that the mildew resistance puts some pressure on the fertility of male wheat plants and subsequently it takes longer to fertilize the female plants. This gives ergot more time to infect the plants. This turn of events was hard to foresee and needed the outdoor research, as Simon Zeller states in the article. Other voices, like Dirk Dobbelaere, Professor for Cell Biology of University of Bern, call it ‘trivial’ that there are different results in green houses and outdoor tests and that the problem of ergot is ‘hundreds of years old’. The NRP 59 is rather undifferentiated in the wrap up of the results on the outdoor research on wheat, even though the outdoor research was a big part of the whole research. Contrariwise, NRP 59 points out the research of the literature studies. Urs Niggli, director of the Research institute of organic agriculture, said: ‘There was a need to point out that gene technology is good’ while at the same time damp results from his own institute: ‘we found no risks of GMPs, but we did not work with the newest strains available’.
In October 2010, the newspaper ‘Sonntagszeitung’ already titled: ‘green gene technology about to fold’, since the cost for outdoor experiments exploded. Militant opponents of green gene technology destroyed the fields of the outdoor tests of GMPs. Thus, the costs to guarantee the safety of the fields were about as high as the costs for the experiments (0,78 CHF for safety for 1 CHF that was spend on research!). The fields needed to be guarded day and night and completely fenced, so the national research council had to provide more money for the outdoor research. After the end of the three year project, it is not yet decided what happens to the fenced research facility, which operation costs about 750 000 CHF a year. On the one hand, the facility can provide know how and technology for the research with GMPs, on the other hand it is not known if further experiments will be done in Switzerland if the moratorium on commercially used plants is extended further and further.
In a way, that was a victory for the opponents of GMP, as illustrated by the quote by Dieter Imboden, president of the National Research Council of the Swiss National funds: 'I do not think that there will be more outdoor tests in Switzerland' . Yet outdoor experiments are important since the result from green houses can be reverted in outdoor experiments or the positive effects can be lower in a less controlled environment such as nature. Without a testing infrastructure the tests are way too expensive. A similar argument can be found in the interview with Prof. Potrykus, who states:” The series of moratoriums decisively contributed to the fact that research with GMP makes no more sense in Switzerland, with all consequences. Switzerland bows out of the development of a technology that is regarded as ‘strategic future technology’ in many other countries. Switzerland once had a leading position on this field (see golden rice project)' , when asked for the consequences of the moratorium. About the consequences, he thinks ‘One must let the Swiss carry the can of their decision. They will realize when it is too late […]’ . Mr Markus Ritter says on the topic: ‘. My position there is to keep the research safe and wait for the breakthrough. Cultivation experiments however, the ones that are prohibited, should be done in big agricultural states not here in Switzerland. But the research is important and we want to preserve it.’ .
He gives another reason to preserve the research in this technology : ‘We are currently running towards many big challenges, like climate change und increasing population. We may in the future be in need of plants that can grow in dry conditions.’
As a response on the final results, the article ‘science has spoken’ was published in ‘Wochenzeitung’ . It quotes again Dieter Imboden who warns: “programs as NRP 59 raises the expectation that science can decide about such polarizing questions. Science cannot render such help” . Even though ‘science’ gave a positive answer as a result of NRP, this does not mean there is all of a sudden great acceptance for a technology that raises many fears and doubts in population. Furthermore, scientists do not all agree to the estimated costs and benefits of GMPs, so there is a lot of room for discussion left. Despite of the fact that disagreement is an integral part of research and almost a prerequisite of progress, the dispute about the findings of NRP 59 are not helpful in gaining the populations trust in research results. Even worse, some researchers where confronted with reproaches of belonging to gene technology friendly organizations and therefore be biased. Scientists seemed to be careful since whatever they say may be used as a slightly out of context argument by any site of the discussion. These examples show that the polarization of the public into black and white thinking also reflects on scientists. Prof. Potrykus stated that ‘it is also the medias fault’ that there are ‘a few that are scientifically well informed, but the majority feels ensured in their fears and prejudices because of the continued moratorium. ‘
National Council Markus Ritter argues in a different way as an answer to the question if people are not well informed: ‘The more we are proceeding into the direction of globalization and a highly technological world, the more people want untouched nature, culture and values, and thy try to at least protect their food as an untouched refugium. The say: “No! Everything, but not our food!”‘ . Despite Mr. Ritter sees the ‘large potential’ of GMPs, ‘we now have no hunger in Switzerland; nobody in this country knows the problem of hunger. So the potential is found more in the Third World.’ That explains the answer of Prof. Potrykus, who answers ‘The people that face the danger of their children becoming blind or die due to the lack of vitamin A have no problem with GMPs yet. Never the less Greenpeace etc. work intensively towards changing this fact.’ when being asked: ‘Can the higher acceptance of golden rice in the population of poor countries be explained by the fact that the use of GMP is better communicated? Are the people in those countries informed well enough?’ .

Opinion

To conclude this little excursion into the Swiss genetically modified plant landscape, I want to give my own personal opinion on the topic: With myself having a strong interest in biology, research and technology, of course my view was biased towards the ‘pro’ GMP side. I hope I could block out the bias and give a neutral review of the situation. In addition, I must admit I could also find some prejudices in myself and I could use the opportunity of digging into some material and writing this text to lower or to get rid of them.
To sum it up, the subject of GMPs is nothing science alone can clearly answer. Many social factors need to be considered before deciding what might be right, wrong or best and where it can be used. The matter is not white or black but comes in many shades. The only thing I know for myself is that one should try everything to keep the research in this field up, since it can have many positive outcomes for society, even if it is, for many reasons, at the moment not yet ready to be fully established in society.

References

http://www.nfp59.ch/d_index.cfm

(*) Peter, M., Lindfeld, A. and Nentwig, W. (2010): Does GM wheat affect saprophagous Diptera species (Drosophilidae, Phoridae)? Pedobiologia, doi: 10.1016/j.pedo.2009.12.006 (als PDF beim SNF erhältlich; E-Mail: pri@snf.ch)
(**) von Burg, S., Müller, C. B. and Romeis, J. (2010): Transgenic disease-resistant wheat does not affect the clonal performance of the aphid Metolophium dirhodum Walker. Basic and Applied Ecology, doi: 10.1016/j.baae.2010.02.003 (als PDF beim SNF erhältlich; E-Mail: pri@snf.ch)
http://www.sonntagszeitung.ch/wissen/artikel-detailseite/?newsid=153963
http://www.woz.ch/1236/gentech-moratorium/die-wissenschaft-hat-gesprochen


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