Introduction

    Home

    Team

Project Overview

    Hacking Systems

    Human Pratices

    Lab Diary

    Safety

Plasmid Plug&Play

    Introduction

    Background

    Experiments

    Modeling

    Results

    Parts

Associative Memory
     Network

    Introduction

    Background

    Experiments

    Modeling

    Results

Extras

    SynbioBrasil

    USP and Unesp

    Attributions

    Sponsors

    Acknowledgements

    Photos

Contents 1 Safety 1.1 Would any of your project ideas raise safety issues in terms of researcher, public or environmental safety? 1.2 Do any of the new BioBrick parts (or devices) that you made this year raise any safety issues? 1.3 Is there a local biosafety group, committee, or review board at your institution? If yes, what does your local biosafety group think about your project? 1.4 Do you have any other ideas how to deal with safety issues that could be useful for future iGEM competitions? How could parts, devices and systems be made even safer through biosafety engineering?

Safety

As a part of iGEM safety efforts, we answered some important questions about the subject involving our project:

Would any of your project ideas raise safety issues in terms of researcher, public or environmental safety?

Our projects use parts that do not raise any particular safety issues different from the ones that are already managed in the laboratories involved, the material is sterilized before being discarded. All the team worked using the biosafety protocols and the protection equipment already established in these laboratories.

Do any of the new BioBrick parts (or devices) that you made this year raise any safety issues?

We used the Cre recombinase enzyme. The Cre recombinase isn't a threat by itself, but its action can increase some risks, since it's a recombination enzyme. Its action raises the probability of mutations and recombinations in the bacterial DNA. Anyway, all material is sterilize before being discard so no genetic modified microorganism will be left free.

Is there a local biosafety group, committee, or review board at your institution? If yes, what does your local biosafety group think about your project?

There are biosafety groups in all the four institutes where the laboratories are located. Although there’s no special concern about the safety of our project, the use of safety standard protocols makes sure that any potential danger is minimized at is lowest level.

Do you have any other ideas how to deal with safety issues that could be useful for future iGEM competitions? How could parts, devices and systems be made even safer through biosafety engineering?

The use of specific bar code DNA and other signatures could make easier to discover possible leaks or contamination in the environment.