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From 2012.igem.org

Contents 1 Would any of your project ideas raise safety issues in terms of researcher, public or environmental safety? 1.1 Do any of the new BioBrick parts (or devices) that you made this year raise any safety issues? 1.2 Is there a local biosafety group, committee, or review board at your institution? If yes, what does your local biosafety group think about your project? 1.3 Do you have any other ideas how to deal with safety issues that could be useful for future iGEM competitions? How could parts, devices and systems be made even safer through biosafety engineering?

Would any of your project ideas raise safety issues in terms of researcher, public or environmental safety?

Our projects deal with parts that do not raise safety issues different from the ones that all the laboratories involved already manage and all material is sterilize before being discard. All the team worked using the biosafety rules and equipment already used in these laboratories.

Do any of the new BioBrick parts (or devices) that you made this year raise any safety issues?

We purposed a biobrick using the enzime Cre recombinase . Actually, the Cre recombinase isn't a threat by itself, but we can imagine its action can increase some risks. Since it's a recombination enzime, its action raises the probability of mutations and unpredictable recombinations into the bacteria. Anyway, all material is sterilize before being discard so no genetic modified microorganism will be free.

Is there a local biosafety group, committee, or review board at your institution? If yes, what does your local biosafety group think about your project?

There is biosafety groups in all three institution, although there’s no special concern about the safety of our project. The use of safety standard protocols makes sure that any potential danger is minimized at its lowest level.

Do you have any other ideas how to deal with safety issues that could be useful for future iGEM competitions? How could parts, devices and systems be made even safer through biosafety engineering?

The use of specific bar code DNA’s and other signatures could make easy to discover possible leaks or contamination in the environment .

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