Team:SYSU-Software

From 2012.igem.org

(Difference between revisions)
 
(48 intermediate revisions not shown)
Line 1: Line 1:
 +
<style type="text/css">
 +
.style1 {
 +
color: #525252;
 +
}
 +
.style2 {
 +
font-size: xx-large;
 +
}
 +
</style>
{{:Team:SYSU-Software/menu}}
{{:Team:SYSU-Software/menu}}
-
<html xmlns="http://www.w3.org/1999/xhtml" xml:lang="en" lang="en">
+
<html xmlns="http://www.w3.org/1999/xhtml" xml:lang="en" lang="en" xmlns:m="http://schemas.microsoft.com/office/2004/12/omml" xmlns:v="urn:schemas-microsoft-com:vml" xmlns:o="urn:schemas-microsoft-com:office:office">
<head>
<head>
<title>Team:SYSU-Software</title>
<title>Team:SYSU-Software</title>
<meta http-equiv="Content-Type" content="text/html; charset=utf-8" />
<meta http-equiv="Content-Type" content="text/html; charset=utf-8" />
<meta http-equiv="Content-Style-Type" content="text/css" />
<meta http-equiv="Content-Style-Type" content="text/css" />
-
<link href="https://2012.igem.org/Team:SYSU-Software/style.css?action=raw&ctype=text/css" rel="stylesheet" type="text/css" >
+
<link href="https://2012.igem.org/Team:SYSU-Software/style.css?action=raw&ctype=text/css" rel="stylesheet" type="text/css" ><link href="https://2012.igem.org/Team:SYSU-Software/layout.css?action=raw&ctype=text/css" rel="stylesheet" type="text/css" >
-
<link href="https://2012.igem.org/Team:SYSU-Software/layout.css?action=raw&ctype=text/css" rel="stylesheet" type="text/css" >
+
<script src="https://2012.igem.org/Team:SYSU-Software/js/jquery-1.4.2.min.js?action=raw&ctype=text/javascript" type="text/javascript"></script>
<script src="https://2012.igem.org/Team:SYSU-Software/js/jquery-1.4.2.min.js?action=raw&ctype=text/javascript" type="text/javascript"></script>
<script src="https://2012.igem.org/Team:SYSU-Software/js/jquery.faded.js?action=raw&ctype=text/javascript" type="text/javascript"></script>
<script src="https://2012.igem.org/Team:SYSU-Software/js/jquery.faded.js?action=raw&ctype=text/javascript" type="text/javascript"></script>
Line 25: Line 32:
       <!-- header -->
       <!-- header -->
       <div id="header">
       <div id="header">
-
         <form action="" id="search-form">
+
         <div id="logopic"><font SIZE="3">
-
          <fieldset>
+
<p>
-
          <input type="text" class="text" value="Site Search" onfocus="if(this.value=='Site Search'){this.value=''}" onblur="if(this.value==''){this.value='Site Search'}"/><input type="submit" class="submit" value="" />
+
<img src= https://static.igem.org/mediawiki/igem.org/1/11/5556.png width="300" height="100"></p>
-
          </fieldset>
+
</font>&nbsp;</div>
-
        </form>
+
-
        <div id="logopic"><a href="#"><img src="https://static.igem.org/mediawiki/igem.org/c/c9/Logo.png"  alt=""  width="320px" height="145px"/></a>  
+
-
</div>
+
         <!-- .nav -->
         <!-- .nav -->
         <ul class="nav">
         <ul class="nav">
              
              
           <li><a href="https://2012.igem.org/Team:SYSU-Software/Project" >Project<span>Software Project</span></a></li>
           <li><a href="https://2012.igem.org/Team:SYSU-Software/Project" >Project<span>Software Project</span></a></li>
-
           <li><a href="https://2012.igem.org/Team:SYSU-Software/Team">Team<span>Instructor and members</span></a></li>
+
           <li><a href="https://2012.igem.org/Team:SYSU-Software/Models">
-
          <li><a href="https://2012.igem.org/Team:SYSU-Software/Safety">Safety<span>Human practice and safety</span></a></li>
+
Models<span>Models &amp; Algorithm</span></a></li>
           <li><a href="https://2012.igem.org/Team:SYSU-Software/Tutorial">Tutorial<span>Guidance book and videos</span></a></li>
           <li><a href="https://2012.igem.org/Team:SYSU-Software/Tutorial">Tutorial<span>Guidance book and videos</span></a></li>
-
           <li><a href="https://2012.igem.org/Team:SYSU-Software/Notebook">Notebook<span>Schedule of this project</span></a></li>
+
           <li><a href="https://2012.igem.org/Team:SYSU-Software/Team">Team<span>Instructor and members</span></a></li>
            
            
 +
             
 +
                 
 +
          <li><a href="https://2012.igem.org/Team:SYSU-Software/WorldJamboree">
 +
For Special Awards <span>For World Jamboree awards</span></a><span lang="zh-cn"><span class="style1">
 +
</span></span></li>
 +
          <li><a href="https://2012.igem.org/Team:SYSU-Software/Practice">Tips<span>Human practice, safety...</span></a></li>
         </ul>
         </ul>
Line 46: Line 56:
         <!-- faded slider -->
         <!-- faded slider -->
         <div id="faded">
         <div id="faded">
-
           <ul>
+
           <ul><li>
-
            <li>
+
            <a href="https://2012.igem.org/Team:SYSU-Software/WorldJamboree">
-
             <img src="https://static.igem.org/mediawiki/2012/0/0e/Slidenp1.jpg" alt="" />
+
             <img   src= https://static.igem.org/mediawiki/2012/5/57/Golden-crystal-butterfly.png  alt="" width="494" height="444" ></a>
-
              <strong>creative ideas</strong>
+
           
-
              <a href="#" class="button-alt">click here</a>
+
             </li>
             </li>
 +
         
             <li>
             <li>
-
             <img src="https://static.igem.org/mediawiki/2012/7/73/Slide2.jpg" alt="" />
+
             <img src= https://static.igem.org/mediawiki/igem.org/4/46/Sdgsfsdd3.png alt="" >
-
               <strong>best solutions</strong>
+
               <strong>creative ideas</strong>
-
               <a href="#" class="button-alt">click here</a>
+
               </li>
-
            </li>
+
              
              
 +
           </ul>
           </ul>
           <ul class="controls">
           <ul class="controls">
Line 72: Line 82:
           <div class="wrapper">
           <div class="wrapper">
             <ul class="tabs">
             <ul class="tabs">
-
              <li class="first"><a href="#tab1">Genome Browser</a></li>
+
            <li class="first"><a href="#tab0">Overview</a></li>
-
               <li><a href="#tab2">Regulator&nbsp;Designer</a></li>
+
 
-
               <li><a href="#tab3">Network&nbsp;Illustrator</a></li>
+
              <li style="left: 0px; top: 0px" ><a href="#tab1">Browser</a></li>
-
              <li><a href="#tab4">Simulator</a></li>
+
               <li><a href="#tab2">Biobrick</a></li>
 +
               <li><a href="#tab3">Riboswitch</a></li>
 +
 
 +
<li><a href="#tab5">MetaNetwork</a></li>
 +
              <li><a href="#tab6">Simulator</a></li>
 +
              <li><a href="#tab7">G-Circle</a></li>
 +
              <li><a href="#tab8">Clotho</a></li>
 +
 
 +
 
 +
 
             </ul>
             </ul>
           </div>
           </div>
           <div class="tab_container">
           <div class="tab_container">
 +
          <div id="tab0" class="tab_content">
 +
            <div class="wrapper">
 +
             
 +
                <div class="extra-wrap">
 +
                <p><img class="img-indent" src="https://static.igem.org/mediawiki/igem.org/7/7c/Cvvxx.png" alt="" width="300px" height="230px" style="float: left ;"/>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Synthetic Biology, depending on interdisciplinary knowledge and experience , cooperates wet and dry experiments to create artificial biological systems . Our team has developed a novel software system,
 +
<a href="https://2012.igem.org/Team:SYSU-Software/Project">BiArkit</a>, to facilitate the design and engineering of specially functional systems. For visualization of genomic data and expression level of functional genes, we develop
 +
<a href="https://2012.igem.org/Team:SYSU-Software/Project#r2"><FONT color="blue">GenomeBrowser</FONT></a> and
 +
<a href="https://2012.igem.org/Team:SYSU-Software/Project#r8"><FONT color="blue">G-Circle</FONT></a>  Besides,
 +
<a href="https://2012.igem.org/Team:SYSU-Software/Project#r3"><FONT color="blue">Biobrick</FONT></a> is localized and transformed into searching kit for users to get comprehensive information conveniently. Further,
 +
<a href="https://2012.igem.org/Team:SYSU-Software/Project#r4"><FONT color="blue">Riboswitch</FONT></a> and
 +
<a href="https://2012.igem.org/Team:SYSU-Software/Project#r5"><FONT color="blue">SiRNA</FONT></a> are designed to compute out potential regulatory parts for engineering systems. For processing data from system level,
 +
<a href="https://2012.igem.org/Team:SYSU-Software/Project#r6"><FONT color="blue">MetaNetwork</FONT></a> can illustrate information of various biological pathways on the graphical and user-friendly interface. And
 +
<a href="https://2012.igem.org/Team:SYSU-Software/Project#r7"><FONT color="blue">Simulator</FONT></a> is intended for modifying and simulating genome-scale metabolic models, which involves many kinds of analyses to predict possible results of conditional changes in experiments.All the functional modules have been successfully added to the
 +
<a href="https://2012.igem.org/Team:SYSU-Software/Clotho">Clotho</a> Frame.
 +
<a href="https://2012.igem.org/Team:SYSU-Software/Project" class="link1"  style="float: right ;""><b>read more</b></a></p>
 +
                 
 +
                  <div class="wrapper"></div>
 +
                </div>
 +
              </div>
 +
            </div>
 +
           <div id="tab1" class="tab_content">
           <div id="tab1" class="tab_content">
             <div class="wrapper">
             <div class="wrapper">
-
               <img class="img-indent" src="https://static.igem.org/mediawiki/2012/7/7c/Browser.jpg" alt="" width="300px" height="230px"/>
+
               <img class="img-indent" src="https://static.igem.org/mediawiki/igem.org/3/3e/Genome.png" alt="" width="300px" height="230px"/>
                 <div class="extra-wrap">
                 <div class="extra-wrap">
-
                 <p>With this Genome Browser, users are able to search Biobricks, plasmids and genomes of model microorganisms; at the same time, gene annotations and information of GenBank are presented. The primary protein sequence is also presented according to the DNA sequences. Aside from searching sequences, users can also input or modify the sequences, insert annotation and build target plasmids they need.</p>
+
                 <p>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; This
 +
is the section for sequences information. With this browser, researchers can
 +
surf for genomes from the typical model organisms. Users can locate the  
 +
interested genes in terms of the input items, including name, product or  
 +
coordinate. In addition, new genomes data will be saved on our website as
 +
downloadable contents.</p>
                    
                    
-
                   <div class="wrapper"><a href="#" class="link1"><b>read more</b></a></div>
+
                   <div class="wrapper"><a href="https://2012.igem.org/Team:SYSU-Software/Project#r2" class="link1"><b>read more</b></a></div>
                 </div>
                 </div>
               </div>
               </div>
Line 91: Line 136:
             <div id="tab2" class="tab_content">
             <div id="tab2" class="tab_content">
             <div class="wrapper">
             <div class="wrapper">
-
               <img class="img-indent" src="https://static.igem.org/mediawiki/2012/7/71/Designer.jpg" alt="" width="300px" height="230px"/>
+
               <img class="img-indent" src="https://static.igem.org/mediawiki/igem.org/4/4f/Biobrick.png" alt="" width="300px" height="230px"/>
                 <div class="extra-wrap">
                 <div class="extra-wrap">
-
                 <p>This part of the software focus on the design of regulatory elements of metabolic networks, mainly non-coding RNAs including SiRNA and Riboswitch. When a certain gene or protein is given, the Designer would generate the elements. What’s more, the primary and secondary structure can be predicted and presented in the Designer. The function of structure prediction can be also applied in other non-coding RNAs, for instance, microRNAs.</p>
+
                 <p>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;This is the section for parts information. It can facilitate researchers to search features and functions of Biobricks documented in the Registry of Standard Biological Parts. All of the relevant operations can be completed without connecting with the Internet.</p>                
-
                 
+
                   <div class="wrapper"><a href="https://2012.igem.org/Team:SYSU-Software/Project#r3" class="link1"><b>read more</b></a></div>
-
                   <div class="wrapper"><a href="#" class="link1"><b>read more</b></a></div>
+
                 </div>
                 </div>
               </div>
               </div>
Line 101: Line 145:
             <div id="tab3" class="tab_content">
             <div id="tab3" class="tab_content">
             <div class="wrapper">
             <div class="wrapper">
-
               <img class="img-indent" src="https://static.igem.org/mediawiki/2012/8/8f/Illustrator.jpg" alt="" width="300px" height="230px" />
+
               <img class="img-indent" src="https://static.igem.org/mediawiki/igem.org/a/ad/Riboswitch.png" alt="" width="300px" height="230px" />
                 <div class="extra-wrap">
                 <div class="extra-wrap">
-
                 <p>Relying on the KEGG Pathway database, the Illustrator exports the optimized relevant pathway map of a gene or transcription factor the user interests in. </p>
+
                 <p><span lang="zh-cn">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; </span>
-
                                     <div class="wrapper"><a href="#" class="link1"><b>read more</b></a></div>
+
<span lang="EN-US">This is the section for generating parts
 +
information. It can assist researchers to design the  
 +
sequences and structures of potential riboswitches according
 +
to their inputs and choices of aptamers. Both of the  
 +
up-regulation and down-regulation riboswiches can be
 +
provided by this kit.</span></p>
 +
                                     <div class="wrapper"><a href="https://2012.igem.org/Team:SYSU-Software/Project#r4" class="link1"><b>read more</b></a></div>
                 </div>
                 </div>
               </div>
               </div>
Line 110: Line 160:
             <div id="tab4" class="tab_content">
             <div id="tab4" class="tab_content">
             <div class="wrapper">
             <div class="wrapper">
-
             <img class="img-indent" src="https://static.igem.org/mediawiki/2012/5/55/Simulator.jpg" alt="" width="300px" height="230px" />
+
              <img class="img-indent" src="https://static.igem.org/mediawiki/igem.org/f/f9/Sirna.png" alt="" width="300px" height="230px" />
 +
                <div class="extra-wrap">
 +
                <p><span lang="zh-cn">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; </span>
 +
<span lang="EN-US">This is the section for generating parts
 +
information. It can design another regulator in engineering
 +
biological systems – siRNA. According to the input
 +
sequences, it can figure out the potential siRNA
 +
automatically.</span></p>
 +
                                    <div class="wrapper"><a href="https://2012.igem.org/Team:SYSU-Software/Project#r5" class="link1"><b>read more</b></a></div>
 +
                </div>
 +
              </div>
 +
            </div>
 +
            <div id="tab5" class="tab_content">
 +
             <div class="wrapper">
 +
              <img class="img-indent" src="https://static.igem.org/mediawiki/igem.org/b/b2/Designer.png" alt="" width="300px" height="230px" />
 +
                <div class="extra-wrap">
 +
                <p><span lang="zh-cn">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; </span>
 +
<span lang="EN-US">This is the section for system information. Given the friendly interface, researchers can explore and acquire their interested gene’s relevant pathways and networks in one map. Users can even drag every graphic element in the maps to check the information conveniently and effectively.</span></p>
 +
                                    <div class="wrapper"><a href="https://2012.igem.org/Team:SYSU-Software/Project#r6" class="link1"><b>read more</b></a></div>
 +
                </div>
 +
              </div>
 +
            </div>
 +
            <div id="tab6" class="tab_content">
 +
            <div class="wrapper">
 +
             
 +
                <div class="extra-wrap"><img class="img-indent" src="https://static.igem.org/mediawiki/igem.org/6/6b/Simulator.png" alt="" width="300px" height="230px" style="float: left ;"/>
 +
                <p><span lang="zh-cn">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; </span>
 +
<span lang="EN-US">This is the section for generating system
 +
information. Based on the reconstruction of genome-scale
 +
models, researcher can use this kit to edit the existent
 +
models according to their needs. Then, they can choose
 +
different combination of analysis to predict effect from a
 +
intended loss-of –function mutation, find necessary and
 +
basic genes maintaining the whole system, predict phenotypic
 +
behavior under the given environmental conditions and
 +
interpret the coupled reaction activities.</span></p>
 +
                                    <div class="wrapper"><a href="https://2012.igem.org/Team:SYSU-Software/Project#r7" class="link1"><b>read more</b></a></div>
 +
                </div>
 +
              </div>
 +
            </div>
 +
<div id="tab8" class="tab_content">
 +
            <div class="wrapper">
 +
             
 +
                <div class="extra-wrap">
 +
<img class="img-indent" src="http://www.autodeskresearch.com/img/header_projects_clotho.jpg" alt="" width="256" height="230px"  style="float: left ;">
 +
                <p><span lang="zh-cn">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Clotho assists researchers to engineer synthetic biological systems and manage the data which is used to create them. It has been developed as the App environment that anyone can create and share new tools in it. These tools facilitate synthetic biologists to arrange their researches under the computer-based and automated- designed environment.
 +
Thus, to advanced develop the Clotho frame, we have successfully transfer the seven parts of our software, BiArkit, into Apps. Users can choose to employ our software through the Clotho media.</span></p>
 +
                                    <div class="wrapper"><a href="https://2012.igem.org/Team:SYSU-Software/Clotho" class="link1"><b>read more</b></a></div>
 +
                </div>
 +
              </div>
 +
            </div>
 +
 
 +
 
 +
            <div id="tab7" class="tab_content">
 +
            <div class="wrapper">
 +
            <img class="img-indent" src="https://static.igem.org/mediawiki/igem.org/4/43/G-circle.png" alt="" width="300px" height="230px" />
               <div class="extra-wrap">
               <div class="extra-wrap">
-
               <p>Simulator is a tool to analyze target metabolic network in method of flux balance analysis (FBA). The Simulator would help researchers rebuild the metabolic network and search key genes in the network, in order to simplify the synthesis design. Relying on the KEGG Pathway database, a novel rFBA model is formed when regulation-relevant conditions are added into the primitive FBA model, which would help the researchers observe the dynamic change in the metabolic system. Moreover, unlike the mainstream of FBA, the analysis of the Simulator is not based on Matlab and is more convenient for researchers to use.</p>
+
               <p><span lang="zh-cn">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; </span>
-
                 <p class="wrapper"><a href="#" class="link1"><b>read more</b></a></p>
+
<span lang="EN-US">This is the section for sequence information.  
 +
It can illustrate the given genome and the expression level of
 +
genes within it under different environment in one graph. In
 +
addition, we have developed it as one app and integrated it into
 +
<i>Clotho</i>.</span></p>
 +
                 <p class="wrapper"><a href="https://2012.igem.org/Team:SYSU-Software/Project#r8" class="link1"><b>read more</b></a></p>
                 </div>
                 </div>
Line 120: Line 230:
           </div>
           </div>
         </div>
         </div>
 +
 +
 +
            <div id="tab8" class="tab_content">
 +
            </div>
         <!-- .box -->
         <!-- .box -->
         <div class="box">
         <div class="box">
Line 125: Line 239:
           <div class="left-bot-corner">
           <div class="left-bot-corner">
             <div class="inner">
             <div class="inner">
-
               <div class="line-ver">
+
               <div class="">
-
                   <div class="wrapper line-ver1">
+
                   <div class="wrapper ">
-
                     <div class="col-1">
+
                   
-
                      <h2><span lang="zh-cn">Software</span></h2>
+
                     <div >
-
                      <ul class="list1">
+
                      <ul >
-
                        <li><span lang="zh-cn"><a href="#">Download</a> &nbsp;&nbsp;&nbsp;
+
                        <li  style="text-align: center ;"><h2> <span lang="zh-cn">&nbsp;&nbsp; </span>
-
</span></li>
+
<span class="style2">video</span></h2>
-
                        <li><a href="#">Tutorial</a></li>
+
<table>
-
                        <li><span lang="zh-cn"><a href="#">Video</a></span></li>
+
<tr>
-
                        <li><a href="#">FAQs</li>
+
<td>Version 1.00 <span lang="zh-cn">Sept.2012</span></td><td>Version 1.05<span lang="zh-cn">  
-
+
Oct.2012</span></td>
-
                       
+
</tr>
 +
<tr>
 +
<td><iframe width="380" height="320" src="http://www.youtube.com/embed/en_OuQ8Ur_8" frameborder="0" allowfullscreen style="float: left ;margin-right: 10px;"></iframe></td>
 +
<td><iframe width="380" height="320" src="http://www.youtube.com/embed/vgP_uKks2Cg" frameborder="0" allowfullscreen style="float: left "></iframe></td>
 +
</tr>
 +
 
 +
</table>
 +
                                                  </li>
                       </ul>
                       </ul>
-
                      <div class="wrapper"><a href="#" class="link1"><b>read more</b></a></div>
 
-
                    </div>
 
-
                    <div class="col-2">
 
-
                      <h2><span lang="zh-cn">Notebook</span></h2>
 
-
                      <ul class="products-list">
 
-
                        <li class="last">
 
-
                          <img src="https://static.igem.org/mediawiki/2012/0/00/Icon2.jpg" alt="" />
 
-
                          <div class="extra-wrap">
 
-
                            <p>Notebook shows you the schedule we developed this project.</p>
 
-
                            <div class="wrapper"><a href="#" class="link1"><b>read more</b></a></div>
 
-
                          </div>
 
-
                        </li>
 
-
                      </ul>
 
-
                    </div>
 
-
                    <div class="col-3">
 
-
                      <h2><span lang="zh-cn">Contact</span> us</h2>
 
-
                      <p>Click "read more" to get access to contact us.                    </p>
 
-
                      <div class="wrapper"><a href="#" class="link1"><b>read more</b></a></div>
 
                     </div>
                     </div>
 +
                   
                   </div>
                   </div>
                 </div>
                 </div>
Line 166: Line 270:
         <!-- .banners -->
         <!-- .banners -->
         <ul class="banners">
         <ul class="banners">
-
         <li><a href="#"><img src="https://static.igem.org/mediawiki/2012/d/d2/Banner1.gif" alt="" /></a></li>
+
         <li>
-
           <li><a href="#"><img src="https://static.igem.org/mediawiki/2012/f/fd/Banner2.gif" alt="" /></a></li>
+
<img src= "https://static.igem.org/mediawiki/2012/c/ca/Xinke.png" alt="" width="160" height="164" ></a></li>
-
           <li><a href="#"><img src="https://static.igem.org/mediawiki/2012/f/fb/Banner3.gif" alt="" /></a></li>
+
           <li >
-
           <li class="last"><a href="#"><img src="https://static.igem.org/mediawiki/2012/5/5b/Banner4.gif" alt="" /></a></li>
+
<img src= "https://static.igem.org/mediawiki/2012/4/45/Shengke.png" alt="" width="160" height="163" ></a></li>
 +
           <li>
 +
<img src= "https://static.igem.org/mediawiki/2012/0/0c/Shuji.png" alt="" width="152" height="156" ></a></li>
 +
           <li class="last">
 +
<img src="https://static.igem.org/mediawiki/2012/b/b4/Ruanjian.png" alt="" width="167" height="64" style=" margin-top:50px;/></a><a href="#"> </li>
         </ul>
         </ul>
         <!-- /.banners -->
         <!-- /.banners -->

Latest revision as of 04:03, 27 October 2012

<style type="text/css"> .style1 { color: #525252; } .style2 { font-size: xx-large; } </style>

Team:SYSU-Software

      Synthetic Biology, depending on interdisciplinary knowledge and experience , cooperates wet and dry experiments to create artificial biological systems . Our team has developed a novel software system, BiArkit, to facilitate the design and engineering of specially functional systems. For visualization of genomic data and expression level of functional genes, we develop GenomeBrowser and G-Circle Besides, Biobrick is localized and transformed into searching kit for users to get comprehensive information conveniently. Further, Riboswitch and SiRNA are designed to compute out potential regulatory parts for engineering systems. For processing data from system level, MetaNetwork can illustrate information of various biological pathways on the graphical and user-friendly interface. And Simulator is intended for modifying and simulating genome-scale metabolic models, which involves many kinds of analyses to predict possible results of conditional changes in experiments.All the functional modules have been successfully added to the Clotho Frame. read more

      This is the section for sequences information. With this browser, researchers can surf for genomes from the typical model organisms. Users can locate the interested genes in terms of the input items, including name, product or coordinate. In addition, new genomes data will be saved on our website as downloadable contents.

     This is the section for parts information. It can facilitate researchers to search features and functions of Biobricks documented in the Registry of Standard Biological Parts. All of the relevant operations can be completed without connecting with the Internet.

      This is the section for generating parts information. It can assist researchers to design the sequences and structures of potential riboswitches according to their inputs and choices of aptamers. Both of the up-regulation and down-regulation riboswiches can be provided by this kit.

      This is the section for generating parts information. It can design another regulator in engineering biological systems – siRNA. According to the input sequences, it can figure out the potential siRNA automatically.

      This is the section for system information. Given the friendly interface, researchers can explore and acquire their interested gene’s relevant pathways and networks in one map. Users can even drag every graphic element in the maps to check the information conveniently and effectively.

      This is the section for generating system information. Based on the reconstruction of genome-scale models, researcher can use this kit to edit the existent models according to their needs. Then, they can choose different combination of analysis to predict effect from a intended loss-of –function mutation, find necessary and basic genes maintaining the whole system, predict phenotypic behavior under the given environmental conditions and interpret the coupled reaction activities.

      Clotho assists researchers to engineer synthetic biological systems and manage the data which is used to create them. It has been developed as the App environment that anyone can create and share new tools in it. These tools facilitate synthetic biologists to arrange their researches under the computer-based and automated- designed environment. Thus, to advanced develop the Clotho frame, we have successfully transfer the seven parts of our software, BiArkit, into Apps. Users can choose to employ our software through the Clotho media.

      This is the section for sequence information. It can illustrate the given genome and the expression level of genes within it under different environment in one graph. In addition, we have developed it as one app and integrated it into Clotho.

read more

  •    video

    Version 1.00 Sept.2012Version 1.05 Oct.2012