Team:Peking

From 2012.igem.org

(Difference between revisions)
Line 2: Line 2:
</p>
</p>
<h2>Programming Cells to Talk Through Light</h2>
<h2>Programming Cells to Talk Through Light</h2>
-
 
+
<br />
<p>During the last few decades, chemically regulated genetic systems have been thoroughly developed and analyzed. Though remarkable endeavors were made towards this issue, the disadvantages of chemical regulation remain: the high cost of chemical synthesis, the diffusion limits, the insecurity and the limited choices of chemicals. </p>
<p>During the last few decades, chemically regulated genetic systems have been thoroughly developed and analyzed. Though remarkable endeavors were made towards this issue, the disadvantages of chemical regulation remain: the high cost of chemical synthesis, the diffusion limits, the insecurity and the limited choices of chemicals. </p>
-
 
+
<br/>
<p>Such incommodity calls for a new generation of optogenetics expression systems. Since first demonstrated in 2002, the contributions of optogenetics have been far beyond that of neuroscience due to the fact that light is more controllable, compared with chemicals, to regulate molecular and cellular behavior. However, most optogenetics methods rely on laser, which limits their field application.</p>
<p>Such incommodity calls for a new generation of optogenetics expression systems. Since first demonstrated in 2002, the contributions of optogenetics have been far beyond that of neuroscience due to the fact that light is more controllable, compared with chemicals, to regulate molecular and cellular behavior. However, most optogenetics methods rely on laser, which limits their field application.</p>
-
 
+
<br />
<p>This summer, Peking iGEM is endeavoring on developing a new luminescence sensor, which is expected to be sensitive to natural light and even bio-luminescence. Based on the ultrasensitive luminescence sensor, we are trying to program E. coli cells to talk through light. The introduction of light-communication between cells attempts to overcome the limits of chemical regulation mentioned above and accomplish regulation beyond spatial separation. </p>
<p>This summer, Peking iGEM is endeavoring on developing a new luminescence sensor, which is expected to be sensitive to natural light and even bio-luminescence. Based on the ultrasensitive luminescence sensor, we are trying to program E. coli cells to talk through light. The introduction of light-communication between cells attempts to overcome the limits of chemical regulation mentioned above and accomplish regulation beyond spatial separation. </p>
<p>
<p>
</html>
</html>
-
 
-
{| style="color:#1b2c8a;background-color:#0c6;" cellpadding="3" cellspacing="1" border="1" bordercolor="#fff" width="62%" align="center"
 
-
!align="center"|[[Team:Peking|Home]]
 
-
!align="center"|[[Team:Peking/Team|Team]]
 
-
!align="center"|[https://igem.org/Team.cgi?year=2012&team_name=Peking Official Team Profile]
 
-
!align="center"|[[Team:Peking/Project|Project]]
 
-
!align="center"|[[Team:Peking/Parts|Parts Submitted to the Registry]]
 
-
!align="center"|[[Team:Peking/Modeling|Modeling]]
 
-
!align="center"|[[Team:Peking/Notebook|Notebook]]
 
-
!align="center"|[[Team:Peking/Safety|Safety]]
 
-
!align="center"|[[Team:Peking/Attributions|Attributions]]
 
-
|}
 

Revision as of 12:16, 14 July 2012

Programming Cells to Talk Through Light


During the last few decades, chemically regulated genetic systems have been thoroughly developed and analyzed. Though remarkable endeavors were made towards this issue, the disadvantages of chemical regulation remain: the high cost of chemical synthesis, the diffusion limits, the insecurity and the limited choices of chemicals.


Such incommodity calls for a new generation of optogenetics expression systems. Since first demonstrated in 2002, the contributions of optogenetics have been far beyond that of neuroscience due to the fact that light is more controllable, compared with chemicals, to regulate molecular and cellular behavior. However, most optogenetics methods rely on laser, which limits their field application.


This summer, Peking iGEM is endeavoring on developing a new luminescence sensor, which is expected to be sensitive to natural light and even bio-luminescence. Based on the ultrasensitive luminescence sensor, we are trying to program E. coli cells to talk through light. The introduction of light-communication between cells attempts to overcome the limits of chemical regulation mentioned above and accomplish regulation beyond spatial separation.