Team:METU

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== '''Biological Carbon monoxide filter:''' ==
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This is a template page. READ THESE INSTRUCTIONS.
 
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You are provided with this team page template with which to start the iGEM season.  You may choose to personalize it to fit your team but keep the same "look." Or you may choose to take your team wiki to a different level and design your own wiki.  You can find some examples <a href="https://2009.igem.org/Help:Template/Examples">HERE</a>.
 
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You <strong>MUST</strong> have all of the pages listed in the menu below with the names specified. PLEASE keep all of your pages within your teams namespace. 
 
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The aim of the Project is to express CODH (Carbon monoxide dehydrogenase) enzyme found in different types of bacteria in cyanobacteria. This enzyme converts CO to CO2 using the reactions below:
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CO2 + 2H+ + 2e- <-> CO + H2O
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Once the CO2 binds, there is a subtle change in the shape of the enzyme that prohibits the CO, when released from the active site, from escaping into the cytoplasm. Being cut off, there is only one escape: move through the molecular tunnel in the enzyme to the A cluster situated by the exit.
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One electron comes from the reduced B cluster, and one electron cones from the reduce C cluster itself.
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This is a reversible reaction; it's conceivable that the toxic effects of CO can be somewhat neutralized by the cell by turning it into CO2. However, since CO is not common in the environment it is doubtful that the bacterium uses the reversed reaction to save itself.
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[[File:metu2012-1.jpg]]
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By the way, the name carbon monoxide dehydrogenase comes from the class of enzymes to which this activity belongs. You'll notice there is no hydrogen on CO2 to dehydrogenate, but if you reverse the reaction above, you can see what is dehydrogenated.
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CODH is important for maintaining current atmospheric conditions. Microbial metabolisms of CO maintains ambient CO at levels safe for other forms of life
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|You can write a background of your team here.  Give us a background of your team, the members, etc.  Or tell us more about something of your choosing.
 
|[[Image:METU_logo.png|200px|right|frame]]
|[[Image:METU_logo.png|200px|right|frame]]
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''Tell us more about your project.  Give us background.  Use this as the abstract of your project.  Be descriptive but concise (1-2 paragraphs)''
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|[[Image:METU_team.png|right|frame|Your team picture]]
|[[Image:METU_team.png|right|frame|Your team picture]]
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Revision as of 19:51, 16 July 2012

Biological Carbon monoxide filter:

The aim of the Project is to express CODH (Carbon monoxide dehydrogenase) enzyme found in different types of bacteria in cyanobacteria. This enzyme converts CO to CO2 using the reactions below:

CO2 + 2H+ + 2e- <-> CO + H2O

Once the CO2 binds, there is a subtle change in the shape of the enzyme that prohibits the CO, when released from the active site, from escaping into the cytoplasm. Being cut off, there is only one escape: move through the molecular tunnel in the enzyme to the A cluster situated by the exit.

One electron comes from the reduced B cluster, and one electron cones from the reduce C cluster itself.

This is a reversible reaction; it's conceivable that the toxic effects of CO can be somewhat neutralized by the cell by turning it into CO2. However, since CO is not common in the environment it is doubtful that the bacterium uses the reversed reaction to save itself.


Metu2012-1.jpg

By the way, the name carbon monoxide dehydrogenase comes from the class of enzymes to which this activity belongs. You'll notice there is no hydrogen on CO2 to dehydrogenate, but if you reverse the reaction above, you can see what is dehydrogenated.

CODH is important for maintaining current atmospheric conditions. Microbial metabolisms of CO maintains ambient CO at levels safe for other forms of life

METU logo.png
Your team picture
Team METU


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