Team:Amsterdam

From 2012.igem.org

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| <font color=black size=5><center>Abstract</center></font>
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| style="width: 100%;"| <font color=black size=5><center>Medal requirements</center></font>
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'''Multi-sensing genetic devices''' offer great future perspectives for biotechnology, environmental monitoring and medical diagnostics. In light of this we have created an innovative [[Team:Amsterdam/glossary#Methyltransferase|'''DNA-Methylation''']] based '''reporter system''' in E. coli, named Cellular Logbook, that has the potential of simultaneously reporting on significantly more signals than current [[Team:Amsterdam/glossary#Fluorescent_Protein|fluorescence-based systems]] (eg. GFP). The Cellular Logbook can be used to '''detect and store''' the presence of '''any compound''' linked to a transcriptional regulator. This system allows for '''offline monitoring''' by functioning as a '''memory module'''. Assessment of the memory status is performed by [[Team:Amsterdam/glossary#Digestion|digesting]] with [[Team:Amsterdam/glossary#Restriction_Enzyme|restriction endonucleases]] followed by [[Team:Amsterdam/glossary#Gel_Electrophoresis|gel electrophoresis]]. Furthermore, the Cellular Logbook is able to infer the '''time of signal-onset''' or '''signal-intensity''' using the natural dilution of the registered signal’s due to cell division. In short our exciting new memory module could potentially be utilized as a platform for many groundbreaking technologies.
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[[File:Amsterdam_thumbs_up.gif|20px]] <font color="#8C7853">[https://igem.org/Team.cgi?id=874 <font color="#8C7853">Team registration</font>]<br\>
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[[File:Amsterdam_thumbs_up.gif|20px]] Complete judging form <br\>
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[[File:Amsterdam_thumbs_up.gif|20px]] [https://2012.igem.org/Team:Amsterdam <font color="#8C7853">Team Wiki</font>]<br\>
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[[File:Amsterdam_thumbs_down.jpg|20px]] Present a poster and a talk at the iGEM Jamboree <br\>
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[[File:Amsterdam_thumbs_up.gif|20px]] New biobrick <br\></font>
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<font color="#C0C0C0">[[File:Amsterdam_thumbs_up.gif|20px]] Working biobrick <br\>
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[[File:Amsterdam_thumbs_up.gif|20px]] Biobrick characterization <br\> </font>
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<font color="#FFD700">[[File:Amsterdam_thumbs_down.jpg|20px]] Improve an existing biobrick <br\>
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[[File:Amsterdam_thumbs_down.jpg|20px]] Collaboration <br\>
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[[File:Amsterdam_thumbs_up.gif|20px]] Human outreach <br\></font>
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| style="width:50%;"| <font color=black size=5><center>Project</center></font>
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| style="width:50%;"| <font color=black size=5><center>Modeling</center></font>
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[https://2012.igem.org/Team:Amsterdam/project/description Project description]<br\>
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[https://2012.igem.org/Team:Amsterdam/project/applications/ Applications]<br\>
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[https://2012.igem.org/Team:Amsterdam/project/FAQ/ Frequently Asked Questions]<br\>
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[https://2012.igem.org/Team:Amsterdam/project/diary/ Diary]<br\>
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[https://2012.igem.org/Team:Amsterdam/project/protocols/ Protocols]<br\>
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[https://2012.igem.org/Team:Amsterdam/project/flashPOC1 Flash Animation for the Proof of Concept]<br\>
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There are no models online yet<br\>
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| style="width:50%;"| <font color=black size=5><center>Tools</center></font>
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| style="width:50%;"| <font color=black size=5><center>Outreach</center></font>
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Plasmid Design Tool: Under production<br\>
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Wiki Editting Tool: Under production<br\>
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[https://2012.igem.org/Team:Amsterdam/safety/questions Safety: questions]<br\>
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[https://2012.igem.org/Team:Amsterdam/safety/components Safety: components]<br\>
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{{Team:Amsterdam/Foot}}
{{Team:Amsterdam/Foot}}

Revision as of 10:52, 23 September 2012

Retrieved from "http://2012.igem.org/Team:Amsterdam"