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From 2012.igem.org

Life is like a box of chocolates. A cheap, thoughtless, perfunctory gift that nobody ever asks for. Unreturnable because all you get back is another box of chocolates. So you're stuck with this undefinable whipped mint crap that you mindlessly wolf down when there's nothing else left to eat. Sure, once in a while there's a peanut butter cup or an English toffee. But they're gone too fast and the taste is... fleeting. So, you end up with nothing but broken bits filled with hardened jelly and teeth-shattering nuts. And if you're desperate enough to eat those, all you got left is an empty box filled with useless brown paper wrappers. (The Cigarette Smoking Man)