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From 2012.igem.org

Motivational drive

Natural cycles have always fascinated mankind, probably due to the mysterious mechanisms involved and the power they exert in our everyday life. Since the dawn of synthetic biology, engineering oscillatory systems has been a recurrent topic, being Ellowitz´s represillator a classical example.Nevertheless, to the date no iGEM team has accomplished the implementation of a robust oscillatory system. We are going to change this.

To do that we designed a synthethic circuit that joints to the endogenous circadian rhythm of synechocystis PCC6803. As a proof of concept we want to engineer the first light-rechargeable biological lamp: Synechocystis PCC 6803 cells that emit light only by night while recovering and producing the substrates in the day.We strongly believe this will serve as an enabling tool to any project wanting to time control a biological behavior independently of the user´s imput.

Furthermore the characterization of this chasis is a fundamental step to explore new systems with minimal inputs in order to replace E. coli to achieve greener industrial processes.