Team:Amsterdam/temp

Home Team Members Ernst Glenn Matias Tania Maarten R. Maarten S. Page 2 Page 3 Project Parts Modelling Outreach

Bacterial populations in their natural form are very capable of storing, processing and acting on stimuli in their environment. Why not exploit these properties in the pursuit of massively parallel computation? The first thing one needs when constructing a computing device is memory to store the results onto. In order to meet this demand we present the cellular logbook which is usable to reliably store whether a signal was detected in E. coli's environment for a time span of its life duration. Expanding this straightforward molecular mechanism, multiple signals can be stored with the prospective of storing up to 64 bits on a single plasmid. Complex cellular behaviour can then be programmed according to the memory status of the cell by way of introducing additional modules transcriptionally controlled by the introduced memory plasmid.