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Project description
Project description
This year, USTC-China iGEMers are providing a novel immune system for engineering
bacteria to fight against the bacteriophage. We hope this artificial line of defeat
with gene circuits can be of practical use in fermentation industry.
Since the fermentation industry occurred, the phage infection has become a big threat
to engineering bacteria. During mass production of dairy products, enzymes, amino
acids, antibiotics and pesticides, the results are unimaginable if the bacterias
are infected by bacteriophages . The bacterias will die abnormally and the infection
will spread quickly. Without any efficient action, tremendous loss will lie ahead.
Nowadays, common strategies for avoiding this catastrophe is to control the conditions
of the fermentation strictly. Also, people keep selecting strains against phages.
But all the strategies are time consuming and far from once for all.
However, the engineering bacteria 2012 USTC-China iGEMers hope to cultivate both
protecting themselves when bacteriophage invades the strain and focusing on producing
products without consuming extra energy when their living environment is safe. In
this case, the quality of fermented products can be guaranteed and the profits of
fermentation industry can be enormously improved.
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