Team:Lyon-INSA/results
From 2012.igem.org
Context and Objectives
Biofilms are responsible for billions of dollars in production losses and treatment costs in the industry every year. Indeed biofilms involve :
Assuming that the environment is over-saturated with harmful chemicals such as biocides, whose long-term health effects still have to be elucidated, there is a great need for novel solutions to reduce detrimental biofilm effects.
Thus, we develop a new generation of solution against biofilms in industry, which allows to reduce :
PROJECT STRATEGY
Our solution is based on engineered bacterial "torpedos" capable of infiltrating, destroying biofilms (KILL) and protecting the cleaned surfaces by either a surfactant coating (COAT option), or by establishment of a positive biofilm ( STICK option).
This tunneling activity of Bacillus subtilis swimmer cells enable to :
Moreover Bacillus strains are non pathogenic and do not cause equipment deteroriation by corrosion.
To sum up, this biocide-alternative strategy provides a money-saving and environementally friendly solution for the control of unwanted biofilm