Team:UCSF/Split Pathway

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Violacein: A Path Divided

Today’s industries are increasingly reliant on the biological production of fuels, drugs, and other materials, bacteria among the foremost type of organism used. However bacterial production has its limits; large and complicated molecules impose a heavy metabolic burden on cells, and production is limited by the fitness cost, or the decreased health of the concerned organism.

These limitations can be circumnavigated by mimicking nature: getting two or more organisms to work together to produce one product.�One way of doing this is splitting the metabolic pathway between two cells.