Team:Hong Kong-CUHK

Check out our FACEBOOK page!

LIGHT OF NO RETURN

Although the sensory technology has been deeply explored and implemented in various means, most of the developed sensors are chemically-dependent promoters which regulate downstream gene expression. We exploited the use of halobacterial sensors, the sensory rhodopsins which are sensitive to a wide spectrum of readily available light source and build a series of sensing systems to control cellular movement and gene regulation. This system can be executed as a fundamental part for further applications, such as cell targeting and refining. Furthermore, to counter the safety issues caused by the leakage of bioengineered cells, this sensing method altogether with the CRISPR/Cas sytem can targart and achieve the cleavage of the transformed plasmid under the stimulation of natural light sources.

Home   |   Team   |   Project   |   Biobricks   |   Human Practice   |   Safety   |   Documentation   |   Acknowledgement

Address: Rm. 184, Science Centre, CUHK
Email: kingchan@cuhk.edu.hk  Tel: (852)-39434420  Fax: (852)-26037246