Team:Amsterdam/shadow/project/overview

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iGEM Amsterdam: Cell Logbook

A chosen sensor gets activated which then promotes transcription of its specific coupled phusion protein, consisting of a ZN-finger and a methyltransferase (ZN-MTase).

Newly translated ZN-MTase moves to and binds to its specific ZN-finger motif binding site and correlating MTase binding site on the introduced plasmid, allowing the MT to methylate its specific motif which is closely located to the Zn-finger binding site. One point of methylation corresponds with 1 bit of information stored on the plasmid.