Antibody module: In the first step, an antibody gene is integrated into the genome of CHO cells.
Antibody module: The CHO-cell produces the antibody and presents it on the cell surface.
Mutation module: The enzyme AID mutates the antibody gene -> maturation
Selection Module: A virus infects cells with high affine antibodies. Those cells survive.
The selected cells are switched to antibody secreting cells with Cre-recombinase.