Reaction | Propensity | Comments |
---|---|---|
Lldr promoter | ||
ø -> Lldr | 0.1 | Constant production of Lldr |
Lldr -> ø | 0.0001 | Constant degradation of Lldr relative to the creation of Lldr giving a molecule number of 1000. |
2 Lldr -> Lldr2 | 3 | Dimerization of Lldr |
Lldr2 -> 2 Lldr | 100 | Undimerization of Lldr giving a majority of Lldr in dimer. |
Lldr2 -> Lldr | 0.0001 | Degradation of Lldr dimer. |
Lldr2 + Lact -> Lldr2Lact | 0.0001 | Binding of lactate to Lldr dimer. Lactate is notconsumed. |
Lldr2Lact -> Lldr2 | 1 | Unbinding of Lactate to dimer |
Lldr2Lact -> Lldr | 0.0001 | Degradation of Lldr in Lldr-Lactate complex |
Lldr2 + pLact -> pLactLldr2 | 1 | Binding of dimer to lld promoter |
pLactLldr2 -> Lldr2 + pLact | 0.1 | Unbinding of dimer to promoter |
pLactLldr2 -> Lldr + pLact | 0.0001 | Degradation of Lldr bound to prooter. |
pLactLldr2 + Lact -> pLactLldr2Lact + Lact | 0.0001 | Binding of lactate to promoter dimer complex. |
pLactLldr2Lact -> pLactLldr2 | 1 | Release of lactate from promoter dimer complex. |
pLactLldr2Lact -> pLactLldr2Lact + mLuxi | 0.005 | Transcription of activated promoter gives LuxI mRNA |
mLuxI -> ø | 0.0025 | Degradation of LuxI mRNA |
mLuxI -> mLuxI + LuxI | 0.0167 | Translation of LuxI mRNA |
LuxI -> ø | 0.0002814 | Degradation of LuxI |
Vgb promoter | ||
ø -> FNR | 1 | Constant production of FNR |
FNR -> ø | 0.001 | Constant degradation of FNR |
ø -> ArcA | 1 | Constant production of ArcA |
ArcA -> ø | 0.001 | Constant degradation of ArcA |
FNR + 2 O2 -> FNRO + 2 O2 | 0.0005 | Oxidation of FNR. Oxygen is not consumed. |
FNR -> FNRO | 0.0001 | Reduction of oxidized FNR. |
FNRO -> ø | 0.001 | Degradation of oxidized FNR. |
ArcA + O2 -> ArcAO + O2 | 0.01 | Oxidation of Arca. Oxygen is not consumed. |
ArcaO -> ArcA | 0.001 | Reduction of oxidized ArcA |
ArcAO -> ø | 0.001 | Degradation of oxidized ArcA |
pOx + FNR -> pOxFNR | 0.1 | Binding of FNR to vgb promoter |
pOxFNR -> pOx + FNR | 0.05 | Unbinding of FNR and vgb promoter |
pOxFNR -> pOx | 0.001 | Degradation of FNR bound to promoter |
pOxFNR + ArcA -> pOxFNRArcA | 0.5 | Binding of ArcA to FNR-promoter complex. |
pOxFNRArcA -> pOxFNR + ArcA | 0.02 | Unbinding of ArcA to FNR-promoter complex. |
pOxFNRArcA -> pOx + FNR | 0.001 | Degradation of ArcA to FNR-promoter complex. |
pOxFNR -> pOxFNR + mLuxR | 0.005 | Transcription of LuxR mRNA |
mLuxR -> ø | 0.00227 | Degradation of LuxR mRNA |
mLuxR -> mLuxR + LuxR | 0.0167 | Translation of LuxR |
LuxR -> ø | 0.0001 | Degradation of LuxR |
Lux promoter | ||
ø -> SAM | 2 | Constant production of S-adenosylmethionine |
SAM -> ø | 0.01 | Constant degradation of SAM |
ø -> hex | 2 | Constant production of 3-oxo-hexanoyl-CoA |
hex -> ø | 0.01 | Constant degradation of hex |
LuxI + SAM -> LuxISAM | 2 | Binding of LuxI and SAM. |
LuxISAM -> LuxI + SAM | 1 | Unbinding of LuxI and SAM |
LuxISAM -> SAM | 0.0002814 | Degradation of LuxI in complex |
LuxISAM + hex -> LuxISAMhex | 2 | Formation of complex of LuxI, SAM and hex |
LuxISAMhex -> LuxISAM + hex | 1 | Complex disasembles |
LuxISAMhex -> SAM + hex | 0.0002814 | LuxI degrades in complex |
LuxISAMhex -> LuxI + HSL | 0.0167 | Homoserine lactone formed from SAM and hex |
HSL -> ø | 0.1 | Diffusion of HSL |
2 LuxR + 2 HSL -> LuxRHSL | 0.002372 | HSL and LuxR forms a complex |
LuxRHSL -> 2 LuxR + 2 HSL | 1 | LuxR-HSL complex disassembles |
LuxRHSL -> LuxR + 2 HSL | 0.0001 | Degradation of LuxR in complex |
pLux + LuxRHSL -> pLuxLuxRHSL | 1 | Binding of LuxRHSL to promoter |
pLuxLuxRHSL -> pLux + LuxRHSL | 0.1 | Unbinding of LuxRHSL and promoter |
pLuxLuxRHSL -> pLux + LuxR + 2 HSL | 0.0001 | Degradation of LuxR in complex |
pLuxLuxRHSL -> pLuxLuxRHSL + mHolin | 0.005 | Transcription of holin mRNA |
mHolin -> ø | 0.0025 | Degradation of holin mRNA |
mHolin -> mHolin + Holin | 0.0167 | Translation of holin mRNA |