| Line 162: | Line 162: | ||
|Degradation of LuxR | |Degradation of LuxR | ||
|- | |- | ||
| + | !colspan="3"|Lldr promoter | ||
| + | |- | ||
| + | |ø -> SAM | ||
| + | |2 | ||
| + | |Constant production of S-adenosylmethionine | ||
| + | |- | ||
| + | |SAM -> ø | ||
| + | |0.01 | ||
| + | |Constant degradation of SAM | ||
| + | |- | ||
| + | |ø -> hex | ||
| + | |2 | ||
| + | |Constant production of 3-oxo-hexanoyl-CoA | ||
| + | |- | ||
| + | |hex -> ø | ||
| + | |0.01 | ||
| + | |Constant degradation of hex | ||
|} | |} | ||
| Reaction | Propensity | Comments |
|---|---|---|
| Lldr promoter | ||
| ø -> Lldr | 0.1 | Constant production of Lldr |
| Lldr -> ø | 0.0001 | Constant degradation of Lldr relative to the creation of Lldr giving a molecule number of 1000. |
| 2 Lldr -> Lldr2 | 3 | Dimerization of Lldr |
| Lldr2 -> 2 Lldr | 100 | Undimerization of Lldr giving a majority of Lldr in dimer. |
| Lldr2 -> Lldr | 0.0001 | Degradation of Lldr dimer. |
| Lldr2 + Lact -> Lldr2Lact | 0.0001 | Binding of lactate to Lldr dimer. Lactate is notconsumed. |
| Lldr2Lact -> Lldr2 | 1 | Unbinding of Lactate to dimer |
| Lldr2Lact -> Lldr | 0.0001 | Degradation of Lldr in Lldr-Lactate complex |
| Lldr2 + pLact -> pLactLldr2 | 1 | Binding of dimer to lld promoter |
| pLactLldr2 -> Lldr2 + pLact | 0.1 | Unbinding of dimer to promoter |
| pLactLldr2 -> Lldr + pLact | 0.0001 | Degradation of Lldr bound to prooter. |
| pLactLldr2 + Lact -> pLactLldr2Lact + Lact | 0.0001 | Binding of lactate to promoter dimer complex. |
| pLactLldr2Lact -> pLactLldr2 | 1 | Release of lactate from promoter dimer complex. |
| pLactLldr2Lact -> pLactLldr2Lact + mLuxi | 0.005 | Transcription of activated promoter gives LuxI mRNA |
| mLuxI -> ø | 0.0025 | Degradation of LuxI mRNA |
| mLuxI -> mLuxI + LuxI | 0.0167 | Translation of LuxI mRNA |
| LuxI -> ø | 0.0002814 | Degradation of LuxI |
| Vgb promoter | ||
| ø -> FNR | 1 | Constant production of FNR |
| FNR -> ø | 0.001 | Constant degradation of FNR |
| ø -> ArcA | 1 | Constant production of ArcA |
| ArcA -> ø | 0.001 | Constant degradation of ArcA |
| FNR + 2 O2 -> FNRO + 2 O2 | 0.0005 | Oxidation of FNR. Oxygen is not consumed. |
| FNR -> FNRO | 0.0001 | Reduction of oxidized FNR. |
| FNRO -> ø | 0.001 | Degradation of oxidized FNR. |
| ArcA + O2 -> ArcAO + O2 | 0.01 | Oxidation of Arca. Oxygen is not consumed. |
| ArcaO -> ArcA | 0.001 | Reduction of oxidized ArcA |
| ArcAO -> ø | 0.001 | Degradation of oxidized ArcA |
| pOx + FNR -> pOxFNR | 0.1 | Binding of FNR to vgb promoter |
| pOxFNR -> pOx + FNR | 0.05 | Unbinding of FNR and vgb promoter |
| pOxFNR -> pOx | 0.001 | Degradation of FNR bound to promoter |
| pOxFNR + ArcA -> pOxFNRArcA | 0.5 | Binding of ArcA to FNR-promoter complex. |
| pOxFNRArcA -> pOxFNR + ArcA | 0.02 | Unbinding of ArcA to FNR-promoter complex. |
| pOxFNRArcA -> pOx + FNR | 0.001 | Degradation of ArcA to FNR-promoter complex. |
| pOxFNR -> pOxFNR + mLuxR | 0.005 | Transcription of LuxR mRNA |
| mLuxR -> ø | 0.00227 | Degradation of LuxR mRNA |
| mLuxR -> mLuxR + LuxR | 0.0167 | Translation of LuxR |
| LuxR -> ø | 0.0001 | Degradation of LuxR |
| Lldr promoter | ||
| ø -> SAM | 2 | Constant production of S-adenosylmethionine |
| SAM -> ø | 0.01 | Constant degradation of SAM |
| ø -> hex | 2 | Constant production of 3-oxo-hexanoyl-CoA |
| hex -> ø | 0.01 | Constant degradation of hex |
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