Team:NRP-UEA-Norwich

From 2012.igem.org

(Difference between revisions)
Line 1: Line 1:
{{UEANRP}}
{{UEANRP}}
-
{{UEANRPSocial}}
+
 
 +
<html><align=center><table width=100% cellspacing=0 cellpadding=0 align=center>
 +
<tr>
 +
<td valign=absmiddle align=center>
 +
<a href="http://twitter.com/nrpigem" target="_blank"><img src="https://static.igem.org/mediawiki/2012/5/5e/WikiTwitter.jpg"></a> <a href="http://www.facebook.com/pages/UEA-iGEM-2012/161749980625611" target="_blank"><img src="https://static.igem.org/mediawiki/2012/7/7e/WikiFB.jpg"></a> <a href="http://ueaigem.tumblr.com" target="_blank"><img src="https://static.igem.org/mediawiki/2012/3/3d/WikiTum.jpg
 +
"></a> <a href="http://www.youtube.com/user/NRPUEAiGem/videos" target="_blank"><img src="https://static.igem.org/mediawiki/igem.org/9/9e/WikiYT.jpg"></a>
 +
</td>
 +
</tr>
 +
</table></html>
 +
 
<br>
<br>

Revision as of 14:22, 18 July 2012

Header1NewGreen.png

NRP UEA iGEM 2012

 


NRP UEA iGEM Team 2012 Project Outline

The NRP-UEA iGEM2012 Logo

The iGEM 2012 team for the Norwich Research Park and University of East Anglia (NRP UEA) are a group of seven biology-based undergraduate students working in the labs within UEA’s BIO building. We have been looking at the role of nitric oxide (NO) in biological systems and are aiming to produce a BioBrick that can sense NO within an environment, report on the levels, and go on to make relevant and desirable changes.

Possible applications we see for this include; cancer therapeutics, where NO levels are detected and raised above the level at which it aids angiogenesis and into the levels at which it is toxic to a tumour; and environmental aspects, where the bio-sensor may be attached to bioluminescence in order to report levels of NO in soil for instance.

Our first BioBrick will be a hybrid bacterial and mammalian promoter (using PyeaR and NS2E9 elements) which will detect NO levels. We aim to use a chassis of Escherichia coli in order to test our BioBrick before investigating its competency within a Salmonella chassis for future applications within a medical system. We also aim to characterise BioBricks produced by previous iGEM teams, especially those involved with sensing physiologically-relevant molecules and reporting with fluorescence or bioluminescence.

We have also looked at various aspects of human outreach and plan to undertake a programme of Synthetic Biology public awareness as well as employing various methods to make our project accessible to those interested outside of the team.

Retrieved from "http://2012.igem.org/Team:NRP-UEA-Norwich"