"
Team:Lyon-INSA/results
From 2012.igem.org
(Difference between revisions)
| Line 37: | Line 37: | ||
A new generation of solution against biofilms in industry <br/> | A new generation of solution against biofilms in industry <br/> | ||
| - | Reduction of cleaning | + | Reduction of harmful chemical reagents in cleaning processes<br/><br/> |
| - | Reduction of | + | Reduction of cleaning costs for industrialists <br/><br/> |
| + | |||
Biofilms are responsible for billions of dollars in production losses and treatment costs in the industry every year:<br/> | Biofilms are responsible for billions of dollars in production losses and treatment costs in the industry every year:<br/> | ||
food spoilage or poisoning in the food industry ;<br/> | food spoilage or poisoning in the food industry ;<br/> | ||
| Line 68: | Line 69: | ||
</div> | </div> | ||
| - | <center><img src="https://static.igem.org/mediawiki/2012/c/cb/ModelBs.jpg" width = 450px/></center><br> | + | <center><img src="https://static.igem.org/mediawiki/2012/c/cb/ModelBs.jpg" width = 450px/></center><br/> |
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
| Line 77: | Line 78: | ||
<li>Delivery of active substance within the biofilm should be facilitated by the tunneling activity of <i> Bacillus </i> swimmer cells</li> | <li>Delivery of active substance within the biofilm should be facilitated by the tunneling activity of <i> Bacillus </i> swimmer cells</li> | ||
| - | <br><br> | + | <br/><br/> |
<i>Bacillus</i> strains are: | <i>Bacillus</i> strains are: | ||
<ul> | <ul> | ||
| Line 83: | Line 84: | ||
<li>do not cause equipment deteroriation by corrosion</li> | <li>do not cause equipment deteroriation by corrosion</li> | ||
| - | <br><br> | + | <br/><br/> |
| - | This biocide-alternative strategy provides an money-saving and environementally friendly solution for the control of unwanted biofilm<br><br> | + | This biocide-alternative strategy provides an money-saving and environementally friendly solution for the control of unwanted biofilm<br/><br/> |
</div> | </div> | ||
| Line 94: | Line 95: | ||
<div class="contenuTexte"> | <div class="contenuTexte"> | ||
| - | <br> | + | <br/> |
| - | <strong> LYSOSTAPHIN</strong> part BBa_K802000<br><br> | + | <strong> LYSOSTAPHIN</strong> part BBa_K802000<br/><br/> |
| - | <center><img src="https://static.igem.org/mediawiki/2012/f/f3/Lyso.jpg" width = 650px/></center><br> | + | <center><img src="https://static.igem.org/mediawiki/2012/f/f3/Lyso.jpg" width = 650px/></center><br/> |
| - | <br> | + | <br/> |
| - | <strong> DISPERSIN</strong> part BBa_K802001<br><br> | + | <strong> DISPERSIN</strong> part BBa_K802001<br/><br/> |
| - | <center><img src="https://static.igem.org/mediawiki/2012/e/e9/Dispersin.jpg" width = 650px/></center><br><br> | + | <center><img src="https://static.igem.org/mediawiki/2012/e/e9/Dispersin.jpg" width = 650px/></center><br/><br/> |
| - | <strong> COMBINED EFFECT</strong> <br><br> | + | <strong> COMBINED EFFECT</strong> <br/><br/> |
| - | <center><img src="https://static.igem.org/mediawiki/2012/8/81/Combined.png" width = 650px/></center><br> | + | <center><img src="https://static.igem.org/mediawiki/2012/8/81/Combined.png" width = 650px/></center><br/> |
</div> | </div> | ||
| Line 114: | Line 115: | ||
<div class="contenuTexte"> | <div class="contenuTexte"> | ||
| - | <br> | + | <br/> |
| - | <strong> SURFACTIN + BIOFILM</strong> part BBa_K802009<br><br> | + | <strong> SURFACTIN + BIOFILM</strong> part BBa_K802009<br/><br/> |
| - | <center><img src="https://static.igem.org/mediawiki/2012/3/31/Coatstick.jpg" width = 650px/></center><br> | + | <center><img src="https://static.igem.org/mediawiki/2012/3/31/Coatstick.jpg" width = 650px/></center><br/> |
<br> | <br> | ||
| - | <strong> AVOID NEW BIOFILM FORMATION</strong> <br><br> | + | <strong> AVOID NEW BIOFILM FORMATION</strong> <br/><br/> |
| - | <strong> NEW RESULTS </strong> <br><br> | + | <strong> NEW RESULTS </strong> <br/><br/> |
| - | <center><img src="https://static.igem.org/mediawiki/2012/2/2e/Combined2.jpg" width = 650px/></center><br> | + | <center><img src="https://static.igem.org/mediawiki/2012/2/2e/Combined2.jpg" width = 650px/></center><br/> |
</div> | </div> | ||
Revision as of 20:28, 25 October 2012
Context and Objectives
A new generation of solution against biofilms in industry
Reduction of harmful chemical reagents in cleaning processes
Reduction of cleaning costs for industrialists
Biofilms are responsible for billions of dollars in production losses and treatment costs in the industry every year:
food spoilage or poisoning in the food industry ;
pathogens' persistence and dispersal in health industry ;
Assuming that the environment is over-saturated with harmful chemicals such as biocides, whose long-term health effects still have to be elucidated, there is a great need for novel solutions to reduce detrimental biofilm effects.
PROJECT STRATEGY
Engineered bacterial "torpedos" capable of infiltrating, destroying biofilms (KILL) and protecting the cleaned surfaces by either a surfactant coating (COAT option), or by establishment of a positive biofilm ( STICK option).
- Inacessible biofilms in pipes should be destroyed
- Delivery of active substance within the biofilm should be facilitated by the tunneling activity of Bacillus swimmer cells
- non pathogenic
- do not cause equipment deteroriation by corrosion
Bacillus strains are:
This biocide-alternative strategy provides an money-saving and environementally friendly solution for the control of unwanted biofilm
KILL : DESTROY BIOFILM
LYSOSTAPHIN part BBa_K802000
DISPERSIN part BBa_K802001
COMBINED EFFECT
COAT or STICK : AVOID NEW BIOFILM FORMATION
SURFACTIN + BIOFILM part BBa_K802009
AVOID NEW BIOFILM FORMATION
NEW RESULTS
