Team:Berkeley/Project/Zippers
From 2012.igem.org
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+ | Protein interaction domains (coiled coils, PDZ, SH3, GBD, etc) have been used by synthetic biologists to oligomerize or localize proteins. In particular, they have been applied to both scaffolding and signaling applications with impressive results. However, the limited number and diversity of well-characterized, orthogonal protein interaction domains restricts the complexity of systems that can be designed. | ||
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Revision as of 00:49, 3 October 2012
Protein interaction domains (coiled coils, PDZ, SH3, GBD, etc) have been used by synthetic biologists to oligomerize or localize proteins. In particular, they have been applied to both scaffolding and signaling applications with impressive results. However, the limited number and diversity of well-characterized, orthogonal protein interaction domains restricts the complexity of systems that can be designed.