"
Team:SUSTC-Shenzhen-B/algorithm
From 2012.igem.org
| Line 16: | Line 16: | ||
<p>TTEC is the first published software to predict terminator efficiency. It takes DNA sequences as input and returns the terminator efficiency value.</p> | <p>TTEC is the first published software to predict terminator efficiency. It takes DNA sequences as input and returns the terminator efficiency value.</p> | ||
<p>To calculate the efficiency of terminator efficiency, there are three steps.</p> | <p>To calculate the efficiency of terminator efficiency, there are three steps.</p> | ||
| - | <p>1.Cut the input terminator sequence into three parts, | + | <p>1.Cut the input terminator sequence into three parts, A tail, stemloop and T tail.</p> |
<p>2.Score the terminator.</p> | <p>2.Score the terminator.</p> | ||
| - | <p>3.Calculate the efficiency of terminator using the simulation | + | <p>3.Calculate the efficiency of terminator using the simulation formula created by our team.</p> |
Revision as of 18:23, 26 September 2012
Overview
TTEC is the first published software to predict terminator efficiency. It takes DNA sequences as input and returns the terminator efficiency value.
To calculate the efficiency of terminator efficiency, there are three steps.
1.Cut the input terminator sequence into three parts, A tail, stemloop and T tail.
2.Score the terminator.
3.Calculate the efficiency of terminator using the simulation formula created by our team.
About Scoring Systems
Three scoring systems mentioned above were all created by researchers to predict rho-independent transcription terminators. If the score of a sequence is good, it is more likely to be a terminator sequence. The score of terminator consists of two parts, corresponding to stemloop and T tail. Here we made a table to show the similarity and difference of these three scoring systems.
To know more about the scoring systems, please click each second menu.
