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Team:SEU O China
From 2012.igem.org
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<p>Our team, SEU_Omega aims to execute a synthetic biology project<br/> | <p>Our team, SEU_Omega aims to execute a synthetic biology project<br/> | ||
based on colony of bacteria.</p> | based on colony of bacteria.</p> | ||
| - | <p>An initial idea concerns the control of the pattern of colony, which would be in the shape of a pentagram. Light sensing would be used as a switch to manipulate the differentiation of cells and the | + | <p>An initial idea concerns the control of the pattern of colony, which would be in the shape of a pentagram. Light sensing would be used as a switch to manipulate the differentiation of cells and the quorum sensing system of AHL would govern the holistic pattern with antisense RNA effecting the division rate.</p> |
<p>Further cellular differentiation would automatically lead<br/> | <p>Further cellular differentiation would automatically lead<br/> | ||
aggregating cells with separated division rates and<br/> | aggregating cells with separated division rates and<br/> | ||
| - | similar phenotype into | + | similar phenotype into specific patterns.</p> |
<p>Available applications may include<br/> | <p>Available applications may include<br/> | ||
bacterial quantitive biosensor,<br/> | bacterial quantitive biosensor,<br/> | ||
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Project Design, Modeling and Experiment together. <br/> | Project Design, Modeling and Experiment together. <br/> | ||
Simulating and confirming the scheme using mathematical<br/> | Simulating and confirming the scheme using mathematical<br/> | ||
| - | + | models, estimating modeling parameters with experiments,<br/> | |
adjusting the experiment plan according to the result of<br/> | adjusting the experiment plan according to the result of<br/> | ||
models, we hope to construct a biology system with such<br/> | models, we hope to construct a biology system with such<br/> | ||
| - | + | an engineering method.</p> | |
</div> | </div> | ||
Revision as of 13:04, 26 September 2012
Our team, SEU_Omega aims to execute a synthetic biology project
based on colony of bacteria.
An initial idea concerns the control of the pattern of colony, which would be in the shape of a pentagram. Light sensing would be used as a switch to manipulate the differentiation of cells and the quorum sensing system of AHL would govern the holistic pattern with antisense RNA effecting the division rate.
Further cellular differentiation would automatically lead
aggregating cells with separated division rates and
similar phenotype into specific patterns.
Available applications may include
bacterial quantitive biosensor,
logical gates, and
so on.
In our project, we tried
to build a biobrick building by combining
Project Design, Modeling and Experiment together.
Simulating and confirming the scheme using mathematical
models, estimating modeling parameters with experiments,
adjusting the experiment plan according to the result of
models, we hope to construct a biology system with such
an engineering method.
