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| <p>We studied the Transcription Terminators which regulate the gene expression. We have developed a free energy based theoretical model to calculate the terminator efficiency from nucleotide sequences. Then, we did some experiment and measured the efficiency of more than 100 terminators to validate our model. Our work is by far the most comprehensive study on terminator efficiency.</p> | | <p>We studied the Transcription Terminators which regulate the gene expression. We have developed a free energy based theoretical model to calculate the terminator efficiency from nucleotide sequences. Then, we did some experiment and measured the efficiency of more than 100 terminators to validate our model. Our work is by far the most comprehensive study on terminator efficiency.</p> |
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- | <h3>Team Abstract</h3>
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- | <img src="https://static.igem.org/mediawiki/2012/2/26/Team_member.JPG" alt="" class="img_fl img_border" />
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- | <p>Our team consists of 7members, who are all sophomores of South University of Science and Technology of China. We are receiving the general education and don’t have our own major now, We gather because of the same hope, the unity.</p>
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- | <a href="https://2012.igem.org/Team:SUSTC-Shenzhen-B/members">More</a>
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| <ul class="tmo_ul_list"> | | <ul class="tmo_ul_list"> |
| <li><a href="http://www.terminatorefficiency.com/"><h3>TTEC-Website</h3></a></li> | | <li><a href="http://www.terminatorefficiency.com/"><h3>TTEC-Website</h3></a></li> |
- | <li><a href="https://2012.igem.org/Team:SUSTC-Shenzhen-B/Tutorial">Tutorial</a></li> | + | <li><a href="https://2012.igem.org/Team:SUSTC-Shenzhen-B/Tutorial"><h3>Tutorial</h3></a></li> |
| </ul> | | </ul> |
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Welcome To TTEC!
TTEC(transcriptional terminator efficiency calculation) is the name of our software.
It is important that transcription is imperfectly terminated at some terminators so that the ratio of the amount of mRNA transcribed from upstream and that from downstream of the terminator is controlled. This is qualified as terminator efficiency.
We studied the Transcription Terminators which regulate the gene expression. We have developed a free energy based theoretical model to calculate the terminator efficiency from nucleotide sequences. Then, we did some experiment and measured the efficiency of more than 100 terminators to validate our model. Our work is by far the most comprehensive study on terminator efficiency.