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Team:Lyon-INSA/results
From 2012.igem.org
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Our solution is based on engineered bacterial "torpedos" capable of infiltrating, destroying biofilms (<strong>KILL</strong>) and protecting the cleaned surfaces by either a surfactant coating (<strong>COAT</strong> option), or by establishment of a positive biofilm (<strong> STICK </strong> option).<br/> | Our solution is based on engineered bacterial "torpedos" capable of infiltrating, destroying biofilms (<strong>KILL</strong>) and protecting the cleaned surfaces by either a surfactant coating (<strong>COAT</strong> option), or by establishment of a positive biofilm (<strong> STICK </strong> option).<br/> | ||
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<center><img src="https://static.igem.org/mediawiki/2012/c/cb/ModelBs.jpg" width = 450px/></center><br/> | <center><img src="https://static.igem.org/mediawiki/2012/c/cb/ModelBs.jpg" width = 450px/></center><br/> | ||
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This tunneling activity of <i>Bacillus subtilis</i> swimmer cells enable to : | This tunneling activity of <i>Bacillus subtilis</i> swimmer cells enable to : | ||
<li>Facilitate the delivery of the active substances within the biofilm</li><br/> | <li>Facilitate the delivery of the active substances within the biofilm</li><br/> | ||
Revision as of 19:14, 26 October 2012
Context and Objectives
Biofilms are responsible for billions of dollars in production losses and treatment costs in the industry every year. Indeed biofilms involve :
Assuming that the environment is over-saturated with harmful chemicals such as biocides, whose long-term health effects still have to be elucidated, there is a great need for novel solutions to reduce detrimental biofilm effects.
Thus, we develop a new generation of solution against biofilms in industry, which allows to reduce :
PROJECT STRATEGY
Our solution is based on engineered bacterial "torpedos" capable of infiltrating, destroying biofilms (KILL) and protecting the cleaned surfaces by either a surfactant coating (COAT option), or by establishment of a positive biofilm ( STICK option).
This tunneling activity of Bacillus subtilis swimmer cells enable to :
Bacillus strains are:
- non pathogenic
- do not cause equipment deteroriation by corrosion
This biocide-alternative strategy provides an money-saving and environementally friendly solution for the control of unwanted biofilm
