Team:Lyon-INSA/results

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A new generation of solution against biofilms in industry <br/>
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Biofilms are responsible for billions of dollars in production losses and treatment costs in the industry every year. Indeed biofilms involve :<br/><br/>
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<li>Food spoilage or poisoning in the food industry<br/>
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<li>Pathogens' persistence and dispersal in health industry<br/>
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<li>Corrosion and diameter reduction of pipelines<br/><br/>
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Assuming that the environment is over-saturated with harmful chemicals such as biocides, whose long-term health effects still have to be elucidated, there is a great need for novel solutions to reduce detrimental biofilm effects.<br/>
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Thus, we develop a new generation of solution against biofilms in industry, which allows to reduce : <br/><br/>
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Reduction of harmful chemical reagents in cleaning processes<br/><br/>
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<li>The use of harmful chemical reagents in cleaning processes<br/>
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Reduction of cleaning costs for industrialists <br/><br/>
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<li>The cleaning costs for industrialists<br/>
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Biofilms are responsible for billions of dollars in production losses and treatment costs in the industry every year:<br/>
 
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food spoilage or poisoning in the food industry ;<br/>
 
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pathogens' persistence and dispersal in health industry ;<br/><br/>
 
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Assuming that the environment is over-saturated with harmful chemicals such as biocides, whose long-term health effects still have to be elucidated, there is a great need for novel solutions to reduce detrimental biofilm effects.<br/><br/>
 
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Revision as of 19:00, 26 October 2012

Context and Objectives



Biofilms are responsible for billions of dollars in production losses and treatment costs in the industry every year. Indeed biofilms involve :

  • Food spoilage or poisoning in the food industry
  • Pathogens' persistence and dispersal in health industry
  • Corrosion and diameter reduction of pipelines

    Assuming that the environment is over-saturated with harmful chemicals such as biocides, whose long-term health effects still have to be elucidated, there is a great need for novel solutions to reduce detrimental biofilm effects.
    Thus, we develop a new generation of solution against biofilms in industry, which allows to reduce :

  • The use of harmful chemical reagents in cleaning processes
  • The cleaning costs for industrialists





    • Click on the title to show/hide the text.

    PROJECT STRATEGY


    Engineered bacterial "torpedos" capable of infiltrating, destroying biofilms (KILL) and protecting the cleaned surfaces by either a surfactant coating (COAT option), or by establishment of a positive biofilm ( STICK option).




    • Inacessible biofilms in pipes should be destroyed
    • Delivery of active substance within the biofilm should be facilitated by the tunneling activity of Bacillus swimmer cells


      • Bacillus strains are:
      • non pathogenic
      • do not cause equipment deteroriation by corrosion


        • This biocide-alternative strategy provides an money-saving and environementally friendly solution for the control of unwanted biofilm

    KILL : DESTROY BIOFILM


    LYSOSTAPHIN part BBa_K802000





    DISPERSIN part BBa_K802001



    COMBINED EFFECT


    COAT or STICK : AVOID NEW BIOFILM FORMATION


    SURFACTIN + BIOFILM part BBa_K802009



    AVOID NEW BIOFILM FORMATION

    NEW RESULTS



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