Team:SJTU-BioX-Shanghai/Project
From 2012.igem.org
(→Why MEMBRANE?) |
(→Why MEMBRANE?) |
||
Line 59: | Line 59: | ||
Why do we choose membrane as our primary scaffold to assemble enzymes? | Why do we choose membrane as our primary scaffold to assemble enzymes? | ||
+ | [[File:12SJTU Why membrane1.png|300px|right|thumb|''Fig.3:'' Natural Scaffold]] | ||
1. '''Natural Scaffold: ''' Different from previous synthesized scaffold, membrane scaffold is an innate one. Besides, there is no limitation on scaffold amount. | 1. '''Natural Scaffold: ''' Different from previous synthesized scaffold, membrane scaffold is an innate one. Besides, there is no limitation on scaffold amount. | ||
- | |||
+ | [[File:12SJTU Why membrane2.jpg|300px|right|thumb|''Fig.4:'' Two-Dimensional Plane]] | ||
2. '''Two-Dimensional Plane: ''' Membrane Scaffold changes restricted the reaction space to a two-dimensional plane, which has been proved to accelerate reaction more sharply than one-dimensional and discrete scaffold. | 2. '''Two-Dimensional Plane: ''' Membrane Scaffold changes restricted the reaction space to a two-dimensional plane, which has been proved to accelerate reaction more sharply than one-dimensional and discrete scaffold. | ||
- | |||
+ | [[File:12SJTU Why membrane3.jpg|300px|right|thumb|''Fig.5:'' Priority to Exportation]] | ||
3. '''Priority to Exportation: ''' Concentration of final products could be effectively increased near the membrane with Membrane Scaffold, which in turn, facilitates the transmembrane transportation. So final products would be more readily to be exported to extracellular media. | 3. '''Priority to Exportation: ''' Concentration of final products could be effectively increased near the membrane with Membrane Scaffold, which in turn, facilitates the transmembrane transportation. So final products would be more readily to be exported to extracellular media. | ||
- | |||
+ | [[File:12SJTU Why membrane4.jpg|300px|right|thumb|''Fig.6:'' Ability to sense signals]] | ||
4. '''Ability to Sense Signals''' Membrane Scaffold provides a platform to directly receive environmental and internal signal. Thus reactions could be dynamically controlled through those signals. | 4. '''Ability to Sense Signals''' Membrane Scaffold provides a platform to directly receive environmental and internal signal. Thus reactions could be dynamically controlled through those signals. | ||
- | |||
==Reference== | ==Reference== |
Revision as of 01:43, 26 October 2012
| ||
|