Team:Potsdam Bioware/slider

From 2012.igem.org

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                       Antibody module: In the first step, an antibody gene is integrated into the genome of CHO cells.
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                       <b>Antibody module: In the first step, an antibody gene is integrated into the genome of CHO cells.</b>
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                       Antibody module: The CHO cell expresses the antibody on the cell surface.
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                       <b>Antibody module: The CHO cell expresses the antibody on the cell surface.</b>
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                     Mutation module: The enzyme AID mutates the antibody gene -> maturation   
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                     <b>Mutation module: The enzyme AID mutates the antibody gene -> maturation</b>  
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                       Selection Module: A virus infects cells with high affine antibodies. Those cells survive.
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                       <b>Selection Module: A virus infects cells with high affine antibodies. These cells survive. </b>
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                       The selected cells are switched to antibody secreting cells with Cre-recombinase.
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                       <b>The selected cells are switched to antibody secreting cells with Cre-recombinase.</b>
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Revision as of 18:39, 26 September 2012

Antibody module: In the first step, an antibody gene is integrated into the genome of CHO cells.

Antibody module: The CHO cell expresses the antibody on the cell surface.

Mutation module: The enzyme AID mutates the antibody gene -> maturation

Selection Module: A virus infects cells with high affine antibodies. These cells survive.

The selected cells are switched to antibody secreting cells with Cre-recombinase.