Team:Potsdam Bioware/slider
From 2012.igem.org
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- | Antibody module: In the first step, an antibody gene is integrated into the genome of CHO cells. | + | <b>Antibody module: In the first step, an antibody gene is integrated into the genome of CHO cells.</b> |
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- | Antibody module: The CHO cell expresses the antibody on the cell surface. | + | <b>Antibody module: The CHO cell expresses the antibody on the cell surface.</b> |
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- | Mutation module: The enzyme AID mutates the antibody gene -> maturation | + | <b>Mutation module: The enzyme AID mutates the antibody gene -> maturation</b> |
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- | Selection Module: A virus infects cells with high affine antibodies. | + | <b>Selection Module: A virus infects cells with high affine antibodies. These cells survive. </b> |
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- | The selected cells are switched to antibody secreting cells with Cre-recombinase. | + | <b>The selected cells are switched to antibody secreting cells with Cre-recombinase.</b> |
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Revision as of 18:39, 26 September 2012