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Team:Nanjing-China
From 2012.igem.org
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<div class="span7 span-pad"> | <div class="span7 span-pad"> | ||
<h2>siGEM at a glance</h2> | <h2>siGEM at a glance</h2> | ||
| - | <p>The essential and expanding roles of small non coding RNAs are becoming clearer to us. More | + | <p class="MsoNormal"><span lang="EN-US">The essential and expanding roles of |
| - | + | small non coding RNAs are becoming clearer to us. More interestingly, plant | |
| - | + | endogenous small RNAs through food intake directly influence gene expression in | |
| + | animals (especially in liver) , as a recent study showed. </span></p> | ||
| + | <p class="MsoNormal"><span lang="EN-US">We took advantage of this | ||
| + | <span class="word">phenomenon</span>, and made engineered lettuce producing | ||
| + | artificial small RNA for therapeutic purpose. We in this case chose PGC1-alpha, | ||
| + | whose high expression in liver can cause insulin resistance, as target. (More... | ||
| + | in project section)</span></p> </div> | ||
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<img src=" https://static.igem.org/mediawiki/igem.org/c/c0/Blank.gif"/> | <img src=" https://static.igem.org/mediawiki/igem.org/c/c0/Blank.gif"/> | ||
Revision as of 00:08, 27 September 2012
Nanjing-China 2012 is working on small interfering genetically engineered machine.
Our team
Engineered lettuce growing
Igem LOGO
siGEM at a glance
The essential and expanding roles of small non coding RNAs are becoming clearer to us. More interestingly, plant endogenous small RNAs through food intake directly influence gene expression in animals (especially in liver) , as a recent study showed.
We took advantage of this phenomenon, and made engineered lettuce producing artificial small RNA for therapeutic purpose. We in this case chose PGC1-alpha, whose high expression in liver can cause insulin resistance, as target. (More... in project section)
Parts at a glance
Our team designed three main modules for our project, si/mi RNA and green plant synthetic biology.They are RNA generating module, T-DNA module, and Barcode 2 module
The essential and expanding roles of small non coding RNAs are becoming clearer to us. More, interestingly, some researchers discovered that plant oriented miRNA works as genetic material transferred from organism to another.
Sharing
In the future, our team or other teams can use parts from the ami-RNA module to construct other plant engineered mechines.
The essential and expanding roles of small non coding RNAs are becoming clearer to us. More, interestingly, some researchers discovered that plant oriented miRNA works as genetic material transferred from organism to another.
