Team:IIT Madras

From 2012.igem.org

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<h1>Faculty Advisor</h1>
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<h1>Nitish Mahapatra</h1>
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<p>We aim to express codon-optimized ligand binding domain of Estrogen Receptor α in conjugation with the ToxR DNA binding domain from Vibrio cholerae in E. coli to separate stereoisomers that have profoundly different impacts on biological systems. Isolation and concentration of specific isomers is of immense biological importance to pharmaceutical industries. We plan to try and simplify this process by separating commercially important compounds using a biological system instead of traditional chemical methods which can be very resource intensive and time consuming. We also plan to develop a high-throughput system for screening of drugs which act on the Estrogen receptor using E. coli. Finally, we wish to provide an efficient means for the bioremediation of endocrine disruptors prevalent in the Indian subcontinent which have an adverse impact on the country’s population. </p>
 
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<h1>Dinesh R</h1>
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<h1>Veerabhadra M V</h1>
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<h1>Avaneesh T/h1>
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<h1>Mullapudi Sri Teja</h1>
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<h1>Chetan Srinath</h1>
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<h1>Nayan Jain</h1>
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<h1>Aditya Sriganesh</h1>
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<h1>Govind Krishna Joshi</h1>
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<h1>Nandita Damaraju</h1>
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<h1>Namit Holay</h1>
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<h1>Kanishka Purushottam Waghmare</h1>
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<h1>Nishita Mohan</h1>
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<h1>Mitan Sutradhar</h1>
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<h1>Mayank NK Choudhary</h1>
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<h1>Prashant adha</h1>
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<h1>Tolkappiyan P</h1>
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<div class = "stu_contents" id = "stu15">
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<h1>Prathyusha konda</h1>
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Revision as of 23:51, 10 September 2012

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Faculty Advisor

Nitish Mahapatra


Advisors

Dinesh R

Veerabhadra M V

Students

Avaneesh T/h1>

Mullapudi Sri Teja

Chetan Srinath

Nayan Jain

Aditya Sriganesh

Govind Krishna Joshi

Nandita Damaraju

Namit Holay

Kanishka Purushottam Waghmare

Nishita Mohan

Mitan Sutradhar

Mayank NK Choudhary

Prashant adha

Tolkappiyan P

Prathyusha konda