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                    <li class='selected'        ><a href="https://2012.igem.org/Team:UC_Davis">Page</a></li>

                 <li class='new'><a href="https://2012.igem.org/wiki/index.php?title=Talk:Team:UC_Davis&amp;action=edit&amp;redlink=1">Discussion</a></li>

                           <li><a href="https://2012.igem.org/wiki/index.php?title=Team:UC_Davis&amp;action=history">History</a></li>

                 <li><a href="https://2012.igem.org/Special:MovePage/Team:UC_Davis">Move</a></li>

                           <li><a href="https://2012.igem.org/wiki/index.php?title=Team:UC_Davis&amp;action=watch">Watch</a></li>

             <li ><a href="./Data.htm ">Data 1</a></li>

            <li ><a href="./Data.htm ">Data 2</a></li>

             <li ><a href="./Data.htm ">Data 3</a></li>

        </ul>

             <li ><a href="Notebook.htm ">Week 1</a></li>

            <li ><a href="Notebook.htm ">Week 2</a></li>

            <li ><a href="Notebook.htm ">Week 3</a></li>

             <li ><a href="https://2012.igem.org/Team:UC_Davis/Project/Strain">Strain</a></li>

             <li ><a href="https://2012.igem.org/Team:UC_Davis/Project/Catalyst">Catalyst</a></li>

             <li ><a href="https://2012.igem.org/Team:UC_Davis/Project/Protein_Engineering" style="font-size:8pt">Protein Engineering</a></li>

         <li ><a href="https://2012.igem.org/Team:UC_Davis" title="Home">Home</a></li>

<h2>News</h2>

<div class="newsAnnouncement">

<ul>

<li>Presented our respective project at the UC San Francisco campus. We interacted with teams from UC Berkeley, UCSF, and Stanford-Brown.  </li>

<li>Requested the protocal from the iGEM Washington 2011 team, July 10th. </li>

<li>Field trip to Yolo County Landfill, June 27th. Met with Ramin Yazdani, the senior civil engineer at the landfill. </li>

<li>Sushi buffet for lunch, June 21st</li>

<li>First day of iGEM meeting, June 18th</li>

</ul>

<a href="http://www.fishersci.com" target="_blank"><img src="https://static.igem.org/mediawiki/2011/a/a4/UCD_Fisher_Logo.gif" width="200"></a>

</div>

<h2>Start a Family</h2>

Got a favorite BioBrick? Check our our <a href="https://2011.igem.org/Team:UC_Davis/PartFamilies">process</a> for expanding basic parts into part families.

</div>

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<h2>Criteria</h2>

View our judging criteria for iGEM 2012 <a href="https://2011.igem.org/Team:UC_Davis/Criteria" style="color:#33FF33;">here</a>.

 

<h1> Data</h1>

The accumulation of plastic products poses a hazard to the environment, as well as humans, through drinking water contamination. This threat led us to develop a degradation pathway to turn the polyethylene terephthalate into different substrates. We produce terephthalic acid and ethylene glycol. Ethylene glycol is a moderately toxic substance, which is oxidized to glycolic acid. The glycolic acid is further oxidized to oxalic acid – a toxic substance that affects the central nervous system via the liver. However, in the environment, the ethylene glycol will be degraded by hydroxyl radicals and in sewage sludge, it is readily biodegradable. Because ethylene glycol must be ingested to pose a problem, researchers take extra precaution to make sure there are no splashes of ethylene glycol in the laboratory and the wastes will be disposed of in the appropriate hazardous waste receptacles. Ethylene glycol can also be a mild irritant if it comes in contact with the skin or if it is inhaled, so researchers wear eye protection as well as gloves and lab coats, and always work with ethylene glycol in the confine of a fume hood. Also, in our constructs, we have produced enzymes that will degrade ethylene glycol into glycoaldehyde and then glycolate. The glycolate has the potential to be turned in to oxaloacetate, a metabolic intermediate. In the environment, ethylene glycol can potentially be toxic within waterways, however the team made sure to dispose of ethylene glycol in a responsible way.  

  </div>

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