Team:Nanjing China Bio/future

From 2012.igem.org

(Difference between revisions)
 
(5 intermediate revisions not shown)
Line 44: Line 44:
/* footer begin */
/* footer begin */
.h49{width:1000px; height:52px; background:url(/wiki/images/7/72/1000_52.jpg) no-repeat; margin:0 auto;}
.h49{width:1000px; height:52px; background:url(/wiki/images/7/72/1000_52.jpg) no-repeat; margin:0 auto;}
-
.w59{width:1000px; height:53px; background:url(/wiki/images/e/ed/1000_53.jpg) repeat-x; margin:0 auto;}
+
.w59{width:1000px; height:53px; background:url(https://static.igem.org/mediawiki/igem.org/e/ed/1000_53.jpg) repeat-x; margin:0 auto;}
.w26{width:100%; height:76px; background:#550303;}
.w26{width:100%; height:76px; background:#550303;}
-
.h18{width:100%; height:18px; background:url(/wiki/images/7/70/51_18.jpg) repeat-x;}
+
.h18{width:100%; height:18px; background:url(https://static.igem.org/mediawiki/igem.org/7/70/51_18.jpg) repeat-x;}
-
.h58{width:1000px; height:58px; background:url(/wiki/images/3/35/1000_58.jpg) no-repeat; margin:0 auto;}
+
.h58{width:1000px; height:58px; background:url(https://static.igem.org/mediawiki/igem.org/3/35/1000_58.jpg) no-repeat; margin:0 auto;}
Line 82: Line 82:
     <div class="head">
     <div class="head">
-
           <div class="h188"><img src="/wiki/images/thumb/a/ab/Notebookimg.jpg/800px-Notebookimg.jpg" width="976" height="188" alt="南京IGEM"/></div>
+
           <div class="h188"><img src="https://static.igem.org/mediawiki/2012/0/00/Projectsimg.jpg" width="976" height="188" alt="南京IGEM"/></div>
           <div class="h45"></div>
           <div class="h45"></div>
           <div class="h80">
           <div class="h80">
Line 101: Line 101:
     <!--content begin-->
     <!--content begin-->
     <div class="con">
     <div class="con">
-
       <div class="place"><span class="p">Background</span><span class="p2"><a href="/Team:Nanjing_China_Bio/index">Home</a> > <a href="/Team:Nanjing_China_Bio/future">future</a></span></div>
+
       <div class="place"><span class="p">Future</span><span class="p2"><a href="/Team:Nanjing_China_Bio/index">Home</a> > <a href="/Team:Nanjing_China_Bio/future">projects</a></span></div>
       <div class="mainul">
       <div class="mainul">
                     <ul>
                     <ul>
-
                         <li><a href="/Team:Nanjing_China_Bio/background" >Background</a></li>
+
                         <li><a href="/Team:Nanjing_China_Bio/projects" >Background</a></li>
                             <li><a href="/Team:Nanjing_China_Bio/future" class="hover">Future</a></li>
                             <li><a href="/Team:Nanjing_China_Bio/future" class="hover">Future</a></li>
                             <li><a href="/Team:Nanjing_China_Bio/method">Method</a></li>   
                             <li><a href="/Team:Nanjing_China_Bio/method">Method</a></li>   
Line 111: Line 111:
       <div class="mainnr">
       <div class="mainnr">
                     <div class="maindl">
                     <div class="maindl">
-
In our experiment of A, we use the background information that the amino acid glucose and other nutrition inside the tumors are much higher than those in normal tissues. We knocked out the gene which encoding arginine of VNP, expecting that after the targeting, the VNP will mostly exist inside the tumor, where the nutrition is the highest. In the future, we will introducing this kind of VNP into the rats with melanoma, to see whether our designed VNP can really work on the prolonging of the rat with cancer. <br><br>
+
In our experiments of A, we used the background information that the concentration of amino acid glucose and other nutrition inside the tumors is much higher than that in normal tissues. We knocked out the gene which encoding arginine of VNP, expecting that after the targeting, the VNP will mostly colonize the tumor areas, where the nutrition is the most abundant. In the future, we will introduce this kind of VNP into the mice with melanoma to see whether our modified VNP can really work on the life prolonging of the mice with cancer.  
-
In our experiment of B, we got some anaerobic promoter, which will improve the bacteria's ability of targeting inside the oxygen-poor cells and tissues including the tumor, where the quantity of oxygen is much lower than the common tissues. In other words, it provides us with a new future direction of cancer therapy ------we can introduce the efficient anaerobic promoter into VNP, which will target inside the tumors and decrease the side-effect of the VNP to the lowest. In order to prove our assumption, we will have our experiments of introducing the VNP with the promoter we designed into the rats with melanoma, in order to see whether the lifetime of them can prolong with the help of our designed promoter. We hope it can really work!
+
<br/>
 +
In our experiments of B, we got some anaerobic promoters, which will improve the bacteria's ability of targeting inside the oxygen-poor cells and tissues including the tumor where the quantity of oxygen is much lower than that in common tissues. In other words, the result provides us with a new future direction of cancer therapy ------we can introduce the efficient anaerobic promoters into VNP, which will target inside the tumors and decrease the side-effect of the VNP to the lowest. In order to prove our assumption, we will have our experiments of introducing the VNP with the promoter we designed into the mice with melanoma to see whether the lifetime of the mice can be prolonged with the help of our designed promoters. We hope it can really work!
                     </div>
                     </div>
                 </div>
                 </div>

Latest revision as of 16:27, 26 September 2012

FutureHome > projects
In our experiments of A, we used the background information that the concentration of amino acid glucose and other nutrition inside the tumors is much higher than that in normal tissues. We knocked out the gene which encoding arginine of VNP, expecting that after the targeting, the VNP will mostly colonize the tumor areas, where the nutrition is the most abundant. In the future, we will introduce this kind of VNP into the mice with melanoma to see whether our modified VNP can really work on the life prolonging of the mice with cancer.
In our experiments of B, we got some anaerobic promoters, which will improve the bacteria's ability of targeting inside the oxygen-poor cells and tissues including the tumor where the quantity of oxygen is much lower than that in common tissues. In other words, the result provides us with a new future direction of cancer therapy ------we can introduce the efficient anaerobic promoters into VNP, which will target inside the tumors and decrease the side-effect of the VNP to the lowest. In order to prove our assumption, we will have our experiments of introducing the VNP with the promoter we designed into the mice with melanoma to see whether the lifetime of the mice can be prolonged with the help of our designed promoters. We hope it can really work!