Team:Michigan

From 2012.igem.org

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    <p> We are designing a switch in <i>E. coli</i> to improve upon an existing protein expression control.
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<h3>A Genetic Toggle Switch Using Recombinases</h3>
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<p>Team Michigan is engineering a novel, tightly controlled and inducible protein expression system in <i>Escherichia coli</i> in order to demonstrate that we can create robust boolean genetic control circuits that do not continuously rely on the presence of signaling compounds. We are using two unidirectional recombinases found in pathogenic <i>Escherichia coli</i>, HbiF and FimE, to manipulate promoter orientation.</p>
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    <p> Induced expression is often too leaky or weak.
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                                          <img src="https://static.igem.org/mediawiki/2012/0/0d/Michigan_%29Random_Team_1.png" alt=""></img>
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    <p> We are using recombinases found usually in pathogenic <i>E. coli</i> to manipulate promoter orientation.
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                                          <img src="https://static.igem.org/mediawiki/2012/a/a0/Michigan_Random_Team_2.png" alt=""></img>
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                                          <img src="https://static.igem.org/mediawiki/2012/b/bc/Michigan_Random_Team_3.png" alt=""></img>
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<!--- The Mission, Experiments --->
 
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{| style="color:#1b2c8a;background-color:#0c6;" cellpadding="3" cellspacing="1" border="1" bordercolor="#fff" width="62%" align="center"
 
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!align="center"|[[Team:Michigan|Home]]
 
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!align="center"|[[Team:Michigan/Team|Team]]
 
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!align="center"|[https://igem.org/Team.cgi?year=2012&team_name=Michigan Official Team Profile]
 
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!align="center"|[[Team:Michigan/Project|Project]]
 
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!align="center"|[[Team:Michigan/Parts|Parts Submitted to the Registry]]
 
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!align="center"|[[Team:Michigan/Modeling|Modeling]]
 
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!align="center"|[[Team:Michigan/Notebook|Notebook]]
 
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!align="center"|[[Team:Michigan/Safety|Safety]]
 
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!align="center"|[[Team:Michigan/Attributions|Attributions]]
 
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Last edit: [[User:Htwong|Htwong]] 20:35, 16 May 2012 (CDT)
 

Latest revision as of 23:54, 3 October 2012

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